SREBF2 Antikörper (Middle Region)

Produktnummer ABIN2792226

Produktdetails anti-SREBF2 Antikörper

Target: SREBF2 (Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SREBF2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PASDSGSQAG FSPYSIDSEP GSPLLDDAKV KDEPDSPPVA LGMVDRSRIL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SREBF2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SREBF2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1141 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SREBF2

Target: SREBF2 (Sterol Regulatory Element Binding Transcription Factor 2 (SREBF2))

Andere Bezeichnung: SREBF2 (SREBF2 Produkte)

Synonyme: SREBF2 antikoerper, srebp2 antikoerper, SREBP2 antikoerper, zgc:158371 antikoerper, AI608257 antikoerper, SREBP-2 antikoerper, SREBP2gc antikoerper, bHLHd2 antikoerper, lop13 antikoerper, nuc antikoerper, Srebf2_retired antikoerper, sterol regulatory element binding transcription factor 2 antikoerper, sterol regulatory element binding factor 2 antikoerper, sterol regulatory element binding transcription factor 2 L homeolog antikoerper, SREBF2 antikoerper, srebf2 antikoerper, Srebf2 antikoerper, srebf2.L antikoerper

Hintergrund: SREBF2 is a ubiquitously expressed transcription factor that controls cholesterol homeostasis by stimulating transcription of sterol-regulated genes. This gene encodes a ubiquitously expressed transcription factor that controls cholesterol homeostasis by stimulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: SREBP2, bHLHd2
Protein Interaction Partner: UBC, ERLIN2, MRPS6, NAE1, MAPK3, MAPK1, PARK7, SCAP, SREBF2, SREBF1, NPAT, HINFP, TRRAP, SUMO2, RNF139, SMAD3, HNF4A, ATF6, KLF13, LZTR1, ABLIM2, ATF7IP, ZDHHC17, COPS5, OS9, PIAS3, CASP8AP2, ARHGEF1, PIAS2, SLC4A4, PIAS1, ZYX, ZMYM2, UBE2I, TTC1, SPTBN1,
Protein Size: 1141

Molekulargewicht: 124 kDa

Gen-ID: 6721

NCBI Accession: NM_004599, NP_004590

UniProt: Q12772

Pathways: Regulation of Lipid Metabolism by PPARalpha