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CDK8 Antikörper (C-Term)

CDK8 Reaktivität: Human, Maus, Zebrafisch (Danio rerio), Hund, Pferd, Kaninchen, Rind (Kuh), Schwein WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2792177
  • Target Alle CDK8 Antikörper anzeigen
    CDK8 (Cyclin-Dependent Kinase 8 (CDK8))
    Bindungsspezifität
    • 14
    • 8
    • 8
    • 7
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 81
    • 38
    • 28
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Zebrafisch (Danio rerio), Hund, Pferd, Kaninchen, Rind (Kuh), Schwein
    Wirt
    • 77
    • 3
    • 1
    Kaninchen
    Klonalität
    • 69
    • 12
    Polyklonal
    Konjugat
    • 40
    • 6
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CDK8 Antikörper ist unkonjugiert
    Applikation
    • 67
    • 34
    • 13
    • 11
    • 10
    • 9
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    GLIMTSDYQR SNPHAAYPNP GPSTSQPQSS MGYSATSQQP PQYSHQTHRY
    Homologie
    Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Zebrafish: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against CDK8. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human CDK8
    Top Product
    Discover our top product CDK8 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 464 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    CDK8 (Cyclin-Dependent Kinase 8 (CDK8))
    Andere Bezeichnung
    CDK8 (CDK8 Produkte)
    Synonyme
    K35 antikoerper, wu:fk95h11 antikoerper, cyclin dependent kinase 8 antikoerper, cyclin-dependent kinase 8 antikoerper, cyclin-dependent kinase 8 S homeolog antikoerper, Cyclin-dependent kinase 8 antikoerper, cyclin dependent kinase 19 antikoerper, CDK8 antikoerper, Cdk8 antikoerper, cdk8 antikoerper, cdk8.S antikoerper, cdk-8 antikoerper, CDK19 antikoerper
    Hintergrund
    The protein encoded by CDK8 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex, which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. This kinase has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH), thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery.
    Alias Symbols: K35
    Protein Interaction Partner: CCNC, MED18, MED15, MED31, MED4, MED13L, MED16, MED6, MED13, MED12, MED24, MED20, MED7, MED27, MED17, MED23, MED21, MED14, HERC2, MED22, MED1, MED11, MED8, MED30, MED10, MED28, MED29, MED9, HNRNPF, CDK8, ERCC3, CCNH, MED19, TCEA1, MBP, CTD, MED26, POLR2A,
    Protein Size: 464
    Molekulargewicht
    53 kDa
    Gen-ID
    1024
    NCBI Accession
    NM_001260, NP_001251
    UniProt
    P49336
    Pathways
    Zellzyklus, Regulation of Lipid Metabolism by PPARalpha
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