TXN Antikörper (C-Term)

Produktnummer ABIN2792061

Produktdetails anti-TXN Antikörper

Target: TXN (Thioredoxin (TXN))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Schwein, Kaninchen, Hund, Meerschweinchen, Pferd, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TXN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: NVIFLEVDVD DCQDVASECE VKCMPTFQFF KKGQKVGEFS GANKEKLEAT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against TXN. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human TXN

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TXN

Target: TXN (Thioredoxin (TXN))

Andere Bezeichnung: TXN (TXN Produkte)

Synonyme: TRDX antikoerper, TRX antikoerper, TRX1 antikoerper, ADF antikoerper, AW550880 antikoerper, Trx1 antikoerper, Txn antikoerper, trx antikoerper, TXN antikoerper, SCM1.18 antikoerper, trxA3 antikoerper, thioredoxin antikoerper, TR-1 antikoerper, Trx-1 antikoerper, thioredoxin antikoerper, thioredoxin 1 antikoerper, thioredoxin L homeolog antikoerper, similar to 44RRORF109c hypothetical protein; similar to bacterial thioredoxin (SwissProt P06544) antikoerper, thioredoxin pseudogene antikoerper, cytosolic thioredoxin Trx1 antikoerper, TXN antikoerper, Txn1 antikoerper, txn.L antikoerper, txn antikoerper, trx antikoerper, SCO0885 antikoerper, PHG25ORF099c antikoerper, LOC100349046 antikoerper, Txn antikoerper, trx1 antikoerper

Hintergrund: TXN participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. It plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. It nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. It induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.
ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55)
Alias Symbols: TRDX, TRX, TRX1
Protein Interaction Partner: NR3C1, GPX1, APEX1, SRP9, PARK2, TXNIP, UBD, Melk, NPM1, PAN2, UBL4A, UBC, DYNLT1, SIAH1, NFE2, MYD88, MYC, MLH1, IFIT3, CDKN1A, ACTN4, GPRASP2, HCVgp1, PRDX1, MAP3K5, SFXN1, UBL5, UBQLN4, TAX1BP3, AHCYL1, SSSCA1, SYNCRIP, WDR1, ATP6V1F, UBE2V1, UBE2D2, S
Protein Size: 105

Molekulargewicht: 11 kDa

Gen-ID: 7295

NCBI Accession: NM_003329, NP_003320

UniProt: P10599

Pathways: Carbohydrate Homeostasis, Cell RedoxHomeostasis