SERF1A Antikörper (N-Term)

Produktnummer ABIN2790697

Produktdetails anti-SERF1A Antikörper

Target: SERF1A (Small EDRK-Rich Factor 1A (Telomeric) (SERF1A))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SERF1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RQKNMKKTQE ISKGKRKEDS LTASQRKQSS GGQKSESKMS AGPHLPLKAP

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SERF1A. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human SERF1A

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 110 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SERF1A

Target: SERF1A (Small EDRK-Rich Factor 1A (Telomeric) (SERF1A))

Andere Bezeichnung: SERF1A (SERF1A Produkte)

Hintergrund: This gene is part of a 500 kb inverted duplication on chromosome 5q13. This duplicated region contains at least four genes and repetitive elements which make it prone to rearrangements and deletions. The repetitiveness and complexity of the sequence have also caused difficulty in determining the organization of this genomic region. The duplication region includes both a telomeric and a centromeric copy of this gene. Deletions of this gene, the telomeric copy, often accompany deletions of the neighboring SMN1 gene in spinal muscular atrophy (SMA) patients, and so it is thought that this gene may be a modifier of the SMA phenotype. The function of this protein is not known, however, it bears low-level homology with the RNA-binding domain of matrin-cyclophilin, a protein which colocalizes with small nuclear ribonucleoproteins (snRNPs) and the SMN1 gene product.
Alias Symbols: 4F5, FAM2A, H4F5, SERF1, SERF1B, SMAM1
Protein Interaction Partner: UBC, APP, PIK3R3,
Protein Size: 110

Molekulargewicht: 12 kDa

Gen-ID: 8293

NCBI Accession: NM_021967, NP_068802

UniProt: O75920