SNX15 Antikörper (N-Term)

Produktnummer ABIN2790379

Produktdetails anti-SNX15 Antikörper

Target: SNX15 (Sorting Nexin 15 (SNX15))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Ziege, Pferd, Rind (Kuh), Hund, Meerschweinchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNX15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RKLHGDLAYT HRNLFRRLEE FPAFPRAQVF GRFEASVIEE RRKGAEDLLR

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SNX15. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human SNX15

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 256 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SNX15

Target: SNX15 (Sorting Nexin 15 (SNX15))

Andere Bezeichnung: SNX15 (SNX15 Produkte)

Synonyme: SNX15 antikoerper, hsaf001435 antikoerper, snx15 antikoerper, MGC154249 antikoerper, HSAF001435 antikoerper, 1500032B08Rik antikoerper, E130013C21Rik antikoerper, sorting nexin 15 antikoerper, sorting nexin 15 S homeolog antikoerper, SNX15 antikoerper, snx15.S antikoerper, snx15 antikoerper, Snx15 antikoerper

Hintergrund: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene.
Alias Symbols: HSAF001435
Protein Interaction Partner: REEP6, RTN4, ARL6IP1, RABAC1, KDM1A, FN1, METTL14, VPS36, SARAF,
Protein Size: 256

Molekulargewicht: 29 kDa

Gen-ID: 29907

NCBI Accession: NM_147777, NP_680086

UniProt: E5KQS6