4-1BBL Antikörper (PE)

Antigen: 4-1BBL

Klonalität: Monoklonal (TKS-1)

Wirt: Ratte

Reaktivität: Maus

Konjugat: PE

Applikation: Durchflusszytometrie (FACS)

Produktnummer: ABIN278979

Produktbeschreibung

Isotyp: IgG2a, kappa chain

Klon: TKS-1

Spezifität: The TKS -1 monoclonal antibody reacts with mouse 4 -1BB Ligand (4 -1BBL), a type II transmembrane protein and a member of the tumor necrosis factor superfamily. 4 -1BBL is expressed by activated antigen presenting cells including B cells and macrophages. Interaction of 4 -1BBL with 4 -1BB (CDw137) is reported to deliver a costimulatory signal important in the T -APC interaction., Mouse

Anwendungen

Applikationshinweise: The TKS -1 antibody has been tested by flow cytometric analysis of resting and 2 -3day (IgM+CD40) -activated mouse splenocytes. This can be used at less than or equal to 1 µg per million cells in a 100 µl total staining volume. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. The TKS -1 antibody has been reported for use in flow cytometric analysis.

Buffer: Phosphate buffer pH 7.2,150 mM NaCl, 0.09% NaN3

Lagerung: Store at 4 °C.DO NOT FREEZE.LIGHT -SENSITIVE MATERIAL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Staining of 3-day unstimulated (left) and 3 day stimulated (anti-mouse IgM + anti-mouse CD40) (right) BALB/c splenocytes with 0.5 µg PE rat IgG2a iso cntrl (cat.ABIN287027) (open histogram) or 0.5 µg PE anti-mouse 4-1BB Ligand (TKS-1) (colored histogram). Total viable cells were used for analysis.

anti-4-1BBL antibody (PE) (Image 2)