Myotilin Antikörper (C-Term)

Produktnummer ABIN2789737

Produktdetails anti-Myotilin Antikörper

Target: Myotilin (MYOT)

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Pferd, Rind (Kuh), Hund, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Myotilin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RNNEMVQFNT DRISLYQDNT GRVTLLIKDV NKKDAGWYTV SAVNEAGVTT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MYOT. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 498 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Myotilin

Target: Myotilin (MYOT)

Andere Bezeichnung: MYOT (MYOT Produkte)

Synonyme: LGMD1 antikoerper, LGMD1A antikoerper, MFM3 antikoerper, TTID antikoerper, TTOD antikoerper, 5530402I04Rik antikoerper, Ttid antikoerper, MYOT antikoerper, ttid antikoerper, myotilin antikoerper, MYOT antikoerper, Myot antikoerper, myot antikoerper

Hintergrund: This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
Alias Symbols: LGMD1, LGMD1A, TTID
Protein Interaction Partner: NME7, TRIM63, TRIM55, GPRASP2, TFG, AXIN1, APP, LRP12, MYOT, FLNA, ACTN1, FLNC, ST7,
Protein Size: 498

Molekulargewicht: 55 kDa

Gen-ID: 9499

NCBI Accession: NM_006790, NP_006781

UniProt: Q9UBF9