SHANK2 Antikörper (C-Term)

Produktnummer ABIN2789713

Produktdetails anti-SHANK2 Antikörper

Target: SHANK2 (SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SHANK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: DLVKQKKSDT PQSPSLNSSQ PTNSADSKKP ASLSNCLPAS FLPPPESFDA

Homologie: Cow: 86%, Dog: 79%, Guinea Pig: 86%, Human: 100%, Mouse: 77%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against SHANK2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1153 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SHANK2

Target: SHANK2 (SH3 and Multiple Ankyrin Repeat Domains 2 (SHANK2))

Andere Bezeichnung: SHANK2 (SHANK2 Produkte)

Synonyme: AUTS17 antikoerper, CORTBP1 antikoerper, CTTNBP1 antikoerper, ProSAP1 antikoerper, SHANK antikoerper, SPANK-3 antikoerper, mKIAA1022 antikoerper, auts17 antikoerper, cortbp1 antikoerper, cttnbp1 antikoerper, prosap1 antikoerper, spank-3 antikoerper, shank2 antikoerper, MGC122482 antikoerper, CortBP1 antikoerper, Spank-3 antikoerper, SHANK2 antikoerper, SH3 and multiple ankyrin repeat domains 2 antikoerper, SH3 and multiple ankyrin repeat domains 2 L homeolog antikoerper, SH3 and multiple ankyrin repeat domains protein 2 antikoerper, SHANK2 antikoerper, Shank2 antikoerper, shank2.L antikoerper, shank2 antikoerper, LOC100438523 antikoerper

Hintergrund: This gene encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density (PSD). Shank proteins contain multiple domains for protein-protein interaction, including ankyrin repeats, an SH3 domain, a PSD-95/Dlg/ZO-1 domain, a sterile alpha motif domain, and a proline-rich region. This particular family member contains a PDZ domain, a consensus sequence for cortactin SH3 domain-binding peptides and a sterile alpha motif. The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain. Two alternative splice variants, encoding distinct isoforms, are reported. Additional splice variants exist but their full-length nature has not been determined.
Alias Symbols: AUTS17, CORTBP1, CTTNBP1, ProSAP1, SHANK, SPANK-3
Protein Interaction Partner: SHARPIN, NLK, LPHN1, DLGAP1, LPHN2, ARHGEF7, BAIAP2, DLG4, BAI2, DNM2, SSTR2, SLC9A3, CTTN, DLGAP3, DLGAP4, DLGAP2, DYNLL2, DYNLL1, MYO5A,
Protein Size: 1153

Molekulargewicht: 126 kDa

Gen-ID: 22941

NCBI Accession: NM_012309