DIAPH1 Antikörper (Diaphanous Homolog 1 (Drosophila)) (C-Term)

Details for Product anti-DIAPH1 Antibody No. ABIN2789663, Anbieter: Anmelden zum Anzeigen
Antigen
  • DIAPH1
  • dia1
  • drf1
  • dfna1
  • diap1
  • lfhl1
  • DIAPH2
  • Diap1
  • D18Wsu154e
  • Dia1
  • Diaph1
  • Drf1
  • mKIAA4062
  • p140mDia
  • DFNA1
  • DIA1
  • DRF1
  • LFHL1
  • hDIA1
  • diaphanous homolog 1 (Drosophila)
  • diaphanous-related formin 1
  • DIAPH1
  • diaph1
  • Diaph1
  • Diap1
Epitop
C-Term
5
5
4
4
3
3
3
2
2
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Human, Maus, Schwein, Kaninchen, Ratte (Rattus)
64
20
12
3
2
1
1
1
1
Wirt
Kaninchen
48
11
8
Klonalität
Polyklonal
Konjugat
Dieser DIAPH1 Antikörper ist unkonjugiert
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
62
18
13
13
11
6
4
1
1
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN975792.
Sequenz TGVMDSLLEA LQSGAAFRRK RGPRQANRKA GCAVTSLLAS ELTKDDAMAA
Homologie Cow: 85%, Dog: 100%, Human: 100%, Mouse: 93%, Pig: 92%, Rabbit: 86%, Rat: 93%
Produktmerkmale This is a rabbit polyclonal antibody against DIAPH1. It was validated on Western Blot.
Reinigung Affinity Purified
Andere Bezeichnung DIAPH1 (DIAPH1 Antibody Abstract)
Hintergrund This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: DFNA1, DIA1, DRF1, FLJ25265, LFHL1, hDIA1
Protein Interaction Partner: UBC, IQGAP1, WWOX, SMEK2, PRPF40A, PTPN23, COPZ1, WBP4, TCERG1, GAS7, NEDD4, KLC1, KIF5B, COPB1, ARCN1, APBB1, KLC4, UBD, gag-pol, VCAM1, GRB2, FN1, CENPA, HSPA4L, MYO1E, DCAF7, SRGAP2, XPO6, CDC7, PAX6, BAIAP2, RAC1, PKD2, RHOA, RHOC,
Protein Size: 1272
Molekulargewicht 141 kDa
Gen-ID 1729
NCBI Accession NM_005219, NP_005210
UniProt O60610
Forschungsgebiet Signaling, Cytoskeleton, Microfilaments
Pathways Sensory Perception of Sound
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 1272 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-Diaphanous Homolog 1 (Drosophila) (DIAPH1) (C-Term) antibody (ABIN2789663) WB Suggested Anti-DIAPH1 Antibody Titration: 1.0 ug/ml Positive Control: HepG2 Whole ...
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