IL5RA Antikörper (N-Term)
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- Target Alle IL5RA Antikörper anzeigen
- IL5RA (Interleukin 5 Receptor, alpha (IL5RA))
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Bindungsspezifität
- N-Term
- Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schwein, Saccharomyces cerevisiae
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IL5RA Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- GLAQVLLQWK PNPDQEQRNV NLEYQVKINA PKEDDYETRI TESKCVTILH
- Homologie
- Cow: 86%, Dog: 79%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 79%, Pig: 86%, Rat: 79%, Yeast: 91%
- Produktmerkmale
- This is a rabbit polyclonal antibody against IL5RA. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product IL5RA Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 420 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- IL5RA (Interleukin 5 Receptor, alpha (IL5RA))
- Andere Bezeichnung
- IL5RA (IL5RA Produkte)
- Synonyme
- MGC86517 antikoerper, IL5RA antikoerper, il5r antikoerper, cdw125 antikoerper, hsil5r3 antikoerper, gpIL-5ra antikoerper, CD125 antikoerper, CDw125 antikoerper, HSIL5R3 antikoerper, IL5R antikoerper, Il5r antikoerper, interleukin 5 receptor subunit alpha L homeolog antikoerper, interleukin 5 receptor subunit alpha antikoerper, interleukin 5 receptor, alpha antikoerper, il5ra.L antikoerper, IL5RA antikoerper, il5ra antikoerper, Il5ra antikoerper
- Hintergrund
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The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.
Alias Symbols: CD125, CDw125, HSIL5R3, IL5R, MGC26560
Protein Interaction Partner: UNC119, SDCBP, IL5, JAK2, JAK1, CSF2RB,
Protein Size: 420 - Molekulargewicht
- 46 kDa
- Gen-ID
- 3568
- NCBI Accession
- NM_175726, NP_783853
- UniProt
- Q01344
- Pathways
- JAK-STAT Signalweg
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