BAG1 Antikörper (N-Term)

Produktnummer ABIN2789514

Produktdetails anti-BAG1 Antikörper

Target: BAG1 (BCL2-Associated Athanogene (BAG1))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BAG1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: QGEEMNRSQE VTRDEESTRS EEVTREEMAA AGLTVTVTHS NEKHDLHVTS

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against BAG1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 345 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu BAG1

Target: BAG1 (BCL2-Associated Athanogene (BAG1))

Andere Bezeichnung: BAG1 (BAG1 Produkte)

Synonyme: BAG-1 antikoerper, HAP antikoerper, RAP46 antikoerper, Rap46 antikoerper, Bag-1 antikoerper, ATBAG1 antikoerper, BCL-2-associated athanogene 1 antikoerper, MSG15.15 antikoerper, MSG15_15 antikoerper, im:7148830 antikoerper, si:dkey-216e9.4 antikoerper, BCL2 associated athanogene 1 antikoerper, putative bcl2-associated athanogene antikoerper, BCL2-associated athanogene 1 antikoerper, Bcl2 associated athanogene 1 antikoerper, BAG family molecular chaperone regulator 1 antikoerper, BCL-2-associated athanogene 1 antikoerper, BAG1 antikoerper, Smp_005900 antikoerper, Bag1 antikoerper, bag-1 antikoerper, LOC781741 antikoerper, bag1 antikoerper

Hintergrund: The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.
Alias Symbols: HAP, RAP46
Protein Interaction Partner: TRIM27, PSMD2, HSPA8, TRIM23, LTN1, DNAJB4, STUB1, DNAJB6, MLF2, DNAJB1, SHFM1, CD44, NIF3L1, RPRD1B, XPO5, OSGEP, PANK4, PEG10, ANP32B, ACTR2, ARPC4, TOM1L1, ZPR1, FUBP1, ANP32A, SH3GL1, GRPEL1, EFTUD1, RPA3, RANGAP1, NR3C1, RAF1, HSPA4, PYGL, ARRB1, UBC
Protein Size: 345

Molekulargewicht: 38 kDa

Gen-ID: 573

NCBI Accession: NM_004323, NP_004314

UniProt: Q99933