TFPI Antikörper (Middle Region)

Produktnummer ABIN2789367

Produktdetails anti-TFPI Antikörper

Target: TFPI (Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor) (TFPI))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus, Kaninchen, Meerschweinchen, Hund, Pferd, Schwein, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TFPI Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: QEKPDFCFLE EDPGICRGYI TRYFYNNQTK QCERFKYGGC LGNMNNFETL

Homologie: Cow: 86%, Dog: 77%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against TFPI. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 304 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TFPI

Target: TFPI (Tissue Factor Pathway Inhibitor (Lipoprotein-Associated Coagulation Inhibitor) (TFPI))

Andere Bezeichnung: TFPI (TFPI Produkte)

Synonyme: EPI antikoerper, LACI antikoerper, TFI antikoerper, TFPI1 antikoerper, A630013F22Rik antikoerper, AW552122 antikoerper, TFPI antikoerper, si:dz44f8.1 antikoerper, tfpib antikoerper, wu:fb92g01 antikoerper, zgc:152844 antikoerper, zgc:158592 antikoerper, tissue factor pathway inhibitor antikoerper, tissue factor pathway inhibitor a antikoerper, TFPI antikoerper, Tfpi antikoerper, tfpia antikoerper

Hintergrund: This gene encodes a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. The encoded protein is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been confirmed.
Alias Symbols: EPI, LACI, TFI, TFPI1
Protein Interaction Partner: SMU1, SF3B1, BCAS2, SAP18, SRSF11, SON, SRSF7, APP, ELAVL1, PRSS3, MMP12, F10, THBS1, MMP7, ELANE, MMP9, MMP8, MMP1,
Protein Size: 304

Molekulargewicht: 33 kDa

Gen-ID: 7035

NCBI Accession: NM_006287, NP_006278

UniProt: P10646