PPP2R4 Antikörper (N-Term)

Produktnummer ABIN2789005

Produktdetails anti-PPP2R4 Antikörper

Target: PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP2R4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: WKRSQAYADY IGFILTLNEG VKGKKLTFEY RVSEMWNEVH EEKEQAAKQS

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PPP2R4. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 358 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PPP2R4

Target: PPP2R4 (Protein Phosphatase 2A Activator, Regulatory Subunit 4 (PPP2R4))

Andere Bezeichnung: PPP2R4 (PPP2R4 Produkte)

Synonyme: PP2A antikoerper, PR53 antikoerper, PTPA antikoerper, 2610042B21Rik antikoerper, C77440 antikoerper, N28142 antikoerper, PTPRA antikoerper, Ppp2r4 antikoerper, fc23d07 antikoerper, ppp2r4 antikoerper, wu:fc23d07 antikoerper, zgc:92766 antikoerper, pp2a antikoerper, ppp2r4.L antikoerper, pr53 antikoerper, ptpa antikoerper, protein phosphatase 2 phosphatase activator antikoerper, protein phosphatase 2 protein activator antikoerper, protein phosphatase 2 phosphatase activator L homeolog antikoerper, PTPA antikoerper, Ptpa antikoerper, ptpa antikoerper, ptpa.L antikoerper

Hintergrund: Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family.
Alias Symbols: MGC2184, PP2A, PR53, PTPA
Protein Interaction Partner: AMOT, MID1, BHLHB9, SP3, STAT1, IER3, UBC, PRKCB, MAPT, EIF4EBP1, RACGAP1, APP, CAV1, AKT1, MAP2K3, MARK2, ATM, STK26, AURKB, CYLD, PPP1CA, HHV8GK18_gp81, SP1, PPP2CA, MDM2, SET, ARRB2, PIM1, PTEN, PPP2R1A, MYOCD, MYLPF, CCT5, CCT8, CCT2, CCT4, CCT7, CCT3
Protein Size: 358

Molekulargewicht: 39 kDa

Gen-ID: 5524

NCBI Accession: NM_178001, NP_821068

UniProt: Q15257

Pathways: PI3K-Akt Signalweg, M Phase, Hepatitis C, Toll-Like Receptors Cascades