Melatonin Receptor 1A Antikörper (C-Term)

Produktnummer ABIN2788825

Produktdetails anti-Melatonin Receptor 1A Antikörper

Target: Melatonin Receptor 1A (MTNR1A)

Bindungsspezifität: C-Term

Reaktivität: Human, Rind (Kuh), Ziege, Hund, Schaf, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Melatonin Receptor 1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GLLNQNFRKE YRRIIVSLCT ARVFFVDSSN DVADRVKWKP SPLMTNNNVV

Homologie: Cow: 79%, Dog: 91%, Goat: 79%, Guinea Pig: 82%, Horse: 83%, Human: 100%, Rabbit: 83%, Sheep: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against MTNR1A. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 350 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Melatonin Receptor 1A

Target: Melatonin Receptor 1A (MTNR1A)

Andere Bezeichnung: MTNR1A (MTNR1A Produkte)

Synonyme: MEL-1A-R antikoerper, MT1 antikoerper, MTNR1A antikoerper, MR antikoerper, MelR antikoerper, MEL1A antikoerper, Mel-1A-R antikoerper, Mel-1A-R-A antikoerper, Mel1a receptor A antikoerper, mel1ar antikoerper, mtnr1ar antikoerper, zgc:110628 antikoerper, melatonin receptor 1A antikoerper, melatonin receptor 1A a antikoerper, MTNR1A antikoerper, Mtnr1a antikoerper, mtnr1aa antikoerper

Hintergrund: This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.
Alias Symbols: MEL-1A-R, MT1
Protein Interaction Partner: VAPB, IRS4, RAP1A, RAC1, HSPA5, GNB1, GNAI3, GNAI2, GNAI1, GNB4, LRRC59, TMEM33, HNRNPA0, RAB10, PGRMC1, PDIA6, FLNA, EEF1G, CNP, CANX, CALR, GPR50, GNA13, DPM1, MTNR1B, MTNR1A, GNA11,
Protein Size: 350

Molekulargewicht: 39 kDa

Gen-ID: 4543

NCBI Accession: NM_005958, NP_005949

UniProt: P48039