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WWOX Antikörper (C-Term)

WWOX Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Schwein, Kaninchen, Hund WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2788787
  • Target Alle WWOX Antikörper anzeigen
    WWOX (WW Domain Containing Oxidoreductase (WWOX))
    Bindungsspezifität
    • 12
    • 11
    • 9
    • 7
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Schwein, Kaninchen, Hund
    Wirt
    • 65
    • 3
    • 2
    Kaninchen
    Klonalität
    • 69
    • 1
    Polyklonal
    Konjugat
    • 42
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser WWOX Antikörper ist unkonjugiert
    Applikation
    • 49
    • 31
    • 13
    • 10
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    DDNPTKPTTR QRYDGSTTAM EILQGRDFTG KVVVVTGANS GIGFETAKSF
    Homologie
    Cow: 100%, Dog: 92%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against WWOX. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Top Product
    Discover our top product WWOX Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 189 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    WWOX (WW Domain Containing Oxidoreductase (WWOX))
    Andere Bezeichnung
    WWOX (WWOX Produkte)
    Synonyme
    CG7221 antikoerper, DmWWOX antikoerper, Dmel\\CG7221 antikoerper, anon-EST:Posey177 antikoerper, GB11795 antikoerper, WWOX antikoerper, D16S432E antikoerper, FOR antikoerper, FRA16D antikoerper, HHCMA56 antikoerper, PRO0128 antikoerper, SDR41C1 antikoerper, WOX1 antikoerper, zgc:55975 antikoerper, 5330426P09Rik antikoerper, 9030416C10Rik antikoerper, WW domain containing oxidoreductase antikoerper, WW domain-containing oxidoreductase antikoerper, Wwox antikoerper, LOC411815 antikoerper, WWOX antikoerper, CpipJ_CPIJ004939 antikoerper, MCYG_01584 antikoerper, VDBG_05631 antikoerper, VDBG_01326 antikoerper, VDBG_06753 antikoerper, Tsp_03967 antikoerper, LOC100284583 antikoerper, wwox antikoerper
    Hintergrund
    WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein which contains 2 WW domains and a short-chain dehydrogenase/reductase domain (SRD). The highest normal expression of this gene is detected in hormonally regulated tissues such as testis, ovary, and prostate. This expression pattern and the presence of an SRD domain suggest a role for this gene in steroid metabolism. The encoded protein is more than 90 % identical to the mouse protein, which is an essential mediator of tumor necrosis factor-alpha-induced apoptosis, suggesting a similar, important role in apoptosis for the human protein. In addition, there is evidence that this gene behaves as a suppressor of tumor growth. Alternative splicing of this gene generates transcript variants that encode different isoforms.
    Alias Symbols: D16S432E, FOR, FRA16D, HHCMA56, PRO0128, SDR41C1, WOX1
    Protein Interaction Partner: ITCH, TRIM28, HUWE1, UBC, ATM, RPRD2, CYFIP1, SPG20, SNRNP200, ACIN1, SLC4A1AP, DHX30, SCAF8, XRN2, GABARAPL2, SEC23IP, HNRNPUL1, DIDO1, CPSF6, SF3B2, SF3A3, SRSF10, USP39, IGF2BP2, IGF2BP3, IGF2BP1, PAICS, PRPF8, CCT2, CCT7, NOP56, DDX17, SEC23A, BAIAP2,
    Protein Size: 189
    Molekulargewicht
    21 kDa
    Gen-ID
    51741
    NCBI Accession
    NM_130791, NP_570607
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