Factor XI Antikörper (C-Term)

Produktnummer ABIN2788664

Produktdetails anti-Factor XI Antikörper

Target: Factor XI (F11) (Coagulation Factor XI (F11))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Factor XI Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RHLCGGSIIG NQWILTAAHC FYGVESPKIL RVYSGILNQS EIKEDTSFFG

Homologie: Cow: 100%, Dog: 79%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 82%, Rabbit: 93%, Rat: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against F11. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human F11

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 625 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Factor XI

Target: Factor XI (F11) (Coagulation Factor XI (F11))

Andere Bezeichnung: F11 (F11 Produkte)

Synonyme: FXI antikoerper, 1600027G01Rik antikoerper, AI503996 antikoerper, Cf11 antikoerper, LRRGT00086 antikoerper, coagulation factor XI antikoerper, F11 antikoerper, CpipJ_CPIJ000593 antikoerper, CpipJ_CPIJ001060 antikoerper, CpipJ_CPIJ002752 antikoerper, CpipJ_CPIJ003631 antikoerper, CpipJ_CPIJ004041 antikoerper, CpipJ_CPIJ004093 antikoerper

Hintergrund: This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality.
Alias Symbols: FXI, MGC141891
Protein Interaction Partner: TFPI2, F11, SERPINA5, SERPINF2, KNG1, F2, HGF,
Protein Size: 625

Molekulargewicht: 70 kDa

Gen-ID: 2160

NCBI Accession: NM_000128, NP_000119

UniProt: P03951