CYP8B1 Antikörper (Middle Region)

Produktnummer ABIN2788348

Produktdetails anti-CYP8B1 Antikörper

Target: CYP8B1 (Cytochrome P450, Family 8, Subfamily B, Polypeptide 1 (CYP8B1))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP8B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SLLWPREWLE VGRLQRLFHK MLSVSHSQEK EGISNWLGNM LQFLREQGVP

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CYP8B1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CYP8B1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 501 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CYP8B1

Target: CYP8B1 (Cytochrome P450, Family 8, Subfamily B, Polypeptide 1 (CYP8B1))

Andere Bezeichnung: CYP8B1 (CYP8B1 Produkte)

Synonyme: MGC64456 antikoerper, CYP8B antikoerper, CP8B antikoerper, CYP12 antikoerper, cytochrome P450 family 8 subfamily B member 1 antikoerper, cytochrome P450 family 8 subfamily B member 1 S homeolog antikoerper, cytochrome P450, family 8, subfamily B, polypeptide 1 antikoerper, cytochrome P450, family 8, subfamily b, polypeptide 1 antikoerper, Cyp8b1 antikoerper, cyp8b1.S antikoerper, CYP8B1 antikoerper

Hintergrund: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one. The balance between these two steroids determines the relative amounts of cholic acid and chenodeoxycholic acid both of which are secreted in the bile and affect the solubility of cholesterol. This gene is unique among the cytochrome P450 genes in that it is intronless.
Alias Symbols: CP8B, CYP12, FLJ17826
Protein Interaction Partner: UBC,
Protein Size: 501

Molekulargewicht: 58 kDa

Gen-ID: 1582

NCBI Accession: NM_004391, NP_004382

UniProt: Q9UNU6