N-Cadherin (CD325) Antikörper (PE)

Antigen: N-Cadherin (CD325)

Klonalität: Monoklonal (8C11)

Wirt: Maus

Reaktivität: Human

Konjugat: PE

Applikation: Durchflusszytometrie (FACS)

Produktnummer: ABIN278828

Produktbeschreibung

Isotyp: IgG1, kappa chain

Klon: 8C11

Spezifität: The 8C11 monoclonal antibody reacts with human CD325, also known as N -Cadherin. CD325 is a 130 kDa member of the Cadherin superfamily, and consists of five extracellular repeats, a transmembrane domain and a cytoplasmic domain. CD325 deficient mice die at day 10 of gestation and embryos display major heart defects and malformed neural tubes and somites. Consistent with this, CD325 has been implicated in several aspects of cardiac development including the precardiac mesoderm, establishment of left -right symmetry and cardiac looping morphogenesis. Furthermore, CD325 is normally involved in inducing cell cycle arrest and its expression is frequently dysregulated in cancer cells., Human

Anwendungen

Applikationshinweise: This 8C11 antibody has been pre -titrated and tested by flow cytometric analysis of HeLa cells. This can be used at 20 µl (0.25 µg) per 100 µl blood (or per 1 million cells in 100 µl total staining volume). This 8C11 antibody has been reported for use in flow cytometric analysis.

Buffer: Phosphate buffered saline, pH 7.2, less than or equal to 0.09% NaN3, BSA and/or gelatin for protein stabilization

Lagerung: Store at 4 °C.DO NOT FREEZE.LIGHT -SENSITIVE MATERIAL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Bilder

Staining of HeLa cells with PE Mouse IgG1, K Iso Cntrl (ABIN287035) (blue histogram) or PE anti-human CD325 (8C11) (purple histogram). Total viable cells were used for analysis.