Adenosine A3 Receptor Antikörper (C-Term)

Produktnummer ABIN2788278

Produktdetails anti-Adenosine A3 Receptor Antikörper

Target: Adenosine A3 Receptor (ADORA3)

Bindungsspezifität: C-Term

Reaktivität: Human, Schwein, Rind (Kuh), Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Adenosine A3 Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: RSCKAPKVVR KADRSRTSIL IICILITGLG IISVISHLTK RRRSQRNRRV

Homologie: Cow: 75%, Horse: 93%, Human: 100%, Pig: 85%, Rabbit: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against ADORA3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ADORA3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 266 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Adenosine A3 Receptor Antikörper (ABIN2788278)

Merighi, Benini, Mirandola, Gessi, Varani, Leung, Maclennan, Baraldi, Borea: "Hypoxia inhibits paclitaxel-induced apoptosis through adenosine-mediated phosphorylation of bad in glioblastoma cells." in: Molecular pharmacology, Vol. 72, Issue 1, pp. 162-72, (2007) (PubMed).

Details zu Adenosine A3 Receptor

Target: Adenosine A3 Receptor (ADORA3)

Andere Bezeichnung: ADORA3 (ADORA3 Produkte)

Synonyme: A3AR antikoerper, AD026 antikoerper, bA552M11.5 antikoerper, ADORA3 antikoerper, 1700001D09Rik antikoerper, 4930578J19Rik antikoerper, A3R antikoerper, AA3R antikoerper, ARA3 antikoerper, Gpcr2 antikoerper, adenosine A3 receptor antikoerper, adenosine receptor A3 antikoerper, ADORA3 antikoerper, Adora3 antikoerper, LOC100603318 antikoerper

Hintergrund: This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: A3AR, AD026, bA552M11.5, RP11-552M11.7
Protein Interaction Partner: YWHAQ, YWHAZ,
Protein Size: 266

Molekulargewicht: 30 kDa

Gen-ID: 140

NCBI Accession: NM_001081976, NP_001075445

UniProt: Q5QNY7

Pathways: Hormone Transport, cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process