PPP1CA Antikörper (N-Term)
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- Target Alle PPP1CA Antikörper anzeigen
- PPP1CA (Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PPP1CA Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- MSDSEKLNLD SIIGRLLEGS RVLTPHCAPV QGSRPGKNVQ LTENEIRGLC
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against PPP1CA. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human PPP1CA
- Top Product
- Discover our top product PPP1CA Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 341 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PPP1CA (Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA))
- Andere Bezeichnung
- PPP1CA (PPP1CA Produkte)
- Synonyme
- PP-1A antikoerper, PP1A antikoerper, PP1alpha antikoerper, PPP1A antikoerper, Ppp1c antikoerper, dism2 antikoerper, ppp1a antikoerper, wu:fc04c08 antikoerper, wu:fc09b07 antikoerper, wu:fc30g11 antikoerper, wu:fe05h08 antikoerper, zgc:85729 antikoerper, Ppp1ca antikoerper, fb18b03 antikoerper, fd20h04 antikoerper, wu:fb18b03 antikoerper, wu:fd20h04 antikoerper, wu:fl22a03 antikoerper, zgc:55744 antikoerper, zgc:76940 antikoerper, protein phosphatase 1 catalytic subunit alpha antikoerper, protein phosphatase 1, catalytic subunit, alpha isoform antikoerper, protein phosphatase 1, catalytic subunit, alpha isozyme L homeolog antikoerper, protein phosphatase 1, catalytic subunit, alpha isozyme antikoerper, protein phosphatase 1, catalytic subunit, alpha isozyme a antikoerper, protein phosphatase 1, catalytic subunit, alpha isozyme b antikoerper, PPP1CA antikoerper, Ppp1ca antikoerper, ppp1ca.L antikoerper, ppp1ca antikoerper, ppp1caa antikoerper, ppp1cab antikoerper
- Hintergrund
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PPP1CA is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory.The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: MGC15877, MGC1674, PP-1A, PPP1A, PP1alpha
Protein Interaction Partner: HUWE1, PPP1R2P3, CSRNP2, CSRNP1, UBC, SUMO2, SUMO3, BRCA1, Kctd20, WWOX, PKM, SCPEP1, TMOD3, MAT2B, STK24, YWHAH, XPO1, TBCB, CAPNS1, ALDH7A1, ASNS, YAP1, LMTK2, RB1, POLR2A, GSK3B, MST1R, IKBKB, CHUK, CTDP1, TNFRSF1A, tat, PPP1R15A, PPP1R13B, PLCL2, CD2B
Protein Size: 341 - Molekulargewicht
- 38 kDa
- Gen-ID
- 5499
- NCBI Accession
- NM_001008709, NP_001008709
- UniProt
- Q07161
- Pathways
- M Phase, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Lipid Metabolism
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