SOD2 Antikörper (N-Term)

Produktnummer ABIN2787727

Produktdetails anti-SOD2 Antikörper

Target: SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Hund, Schaf, Rind (Kuh), Meerschweinchen, Kaninchen, Ziege, Zebrafisch (Danio rerio), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MLSRAVCGTS RQLAPVLGYL GSRQKHSLPD LPYDYGALEP HINAQIMQLH

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against SOD2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SOD2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 222 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SOD2

Target: SOD2 (Superoxide Dismutase 2, Mitochondrial (SOD2))

Andere Bezeichnung: SOD2 (SOD2 Produkte)

Synonyme: LOC100101896 antikoerper, MNSOD antikoerper, GB14346 antikoerper, sod2 antikoerper, MGC88869 antikoerper, Sod2 antikoerper, CG8905 antikoerper, Dmel\\CG8905 antikoerper, Mito SOD antikoerper, Mn SOD antikoerper, Mn-SOD antikoerper, Mn-SOD2 antikoerper, MnSOD antikoerper, MnSODII antikoerper, Mn[2+]SOD antikoerper, SOD antikoerper, SOD-2 antikoerper, SOD2 antikoerper, Sod-2 antikoerper, dSOD2 antikoerper, mitSOD2 antikoerper, mnSOD antikoerper, IPOB antikoerper, MVCD6 antikoerper, cb463 antikoerper, wu:fj33b01 antikoerper, zgc:73051 antikoerper, MnSOD antikoerper, manganese superoxide dismutase antikoerper, superoxide dismutase 2, mitochondrial antikoerper, superoxide dismutase 2 antikoerper, Mn superoxide dismutase antikoerper, Superoxide dismutase 2 (Mn) antikoerper, superoxide dismutase 2 L homeolog antikoerper, BDBG_07234 antikoerper, LOC100101896 antikoerper, MNSOD antikoerper, Sod2 antikoerper, sod2 antikoerper, LbMnSOD4 antikoerper, SOD2 antikoerper, LOC100282741 antikoerper, SOD-2 antikoerper, sod2.L antikoerper

Hintergrund: SOD2 is a member of the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene encoding SOD2 have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer.This gene is a member of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. This protein binds to the superoxide byproducts of oxidative phosphorylation and converts them to hydrogen peroxide and diatomic oxygen. Mutations in this gene have been associated with idiopathic cardiomyopathy (IDC), premature aging, sporadic motor neuron disease, and cancer. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: IPO-B, MNSOD, Mn-SOD, IPOB, MVCD6
Protein Interaction Partner: CYP4F12, UBC, SOD2, SOD1, APP, NABP2, TBL2, ZC3H11A, VAPA, STX7, UBL4A, ALDH5A1, USP36, H2AFX, SUMO1, NOL12, HDHD2, GET4, RPS3A, RAB4A, AURKA,
Protein Size: 222

Molekulargewicht: 24 kDa

Gen-ID: 6648

NCBI Accession: NM_000636, NP_000627

UniProt: P04179

Pathways: Sensory Perception of Sound, Transition Metal Ion Homeostasis, Negative Regulation of intrinsic apoptotic Signaling