GLP2R Antikörper (N-Term)

Produktnummer ABIN2787698

Produktdetails anti-GLP2R Antikörper

Target: GLP2R (Glucagon-Like Peptide 2 Receptor (GLP2R))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLP2R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KLGSSRAGPG RGSAGLLPGV HELPMGIPAP WGTSPLSFHR KCSLWAPGRP

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against GLP2R. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GLP2R

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 553 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-GLP2R Antikörper (ABIN2787698)

Sams, Hastrup, Andersen, Thim: "Naturally occurring glucagon-like peptide-2 (GLP-2) receptors in human intestinal cell lines." in: European journal of pharmacology, Vol. 532, Issue 1-2, pp. 18-23, (2006) (PubMed).

Details zu GLP2R

Target: GLP2R (Glucagon-Like Peptide 2 Receptor (GLP2R))

Andere Bezeichnung: GLP2R (GLP2R Produkte)

Synonyme: 9530092J08Rik antikoerper, GLP-2 antikoerper, glucagon like peptide 2 receptor antikoerper, glucagon-like peptide 2 receptor antikoerper, GLP2R antikoerper, Glp2r antikoerper

Hintergrund: The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans GLP1 receptor. Glucagon-like peptide-2 (GLP2) is a 33-amino acid proglucagon-derived peptide produced by intestinal enteroendocrine cells. Like glucagon-like peptide-1 (GLP1) and glucagon itself, it is derived from the proglucagon peptide encoded by the GCG gene. GLP2 stimulates intestinal growth and upregulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. Moreover, GLP2 prevents intestinal hypoplasia resulting from total parenteral nutrition. GLP2R, a G protein-coupled receptor superfamily member is expressed in the gut and closely related to the glucagon receptor (GCGR) and the receptor for GLP1 (GLP1R). The GLP2 receptor (GLP2R) is a G protein-coupled receptor superfamily member closely related to the glucagon receptor ans GLP1 receptor. Glucagon-like peptide-2 (GLP2) is a 33-amino acid proglucagon-derived peptide produced by intestinal enteroendocrine cells. Like glucagon-like peptide-1 (GLP1) and glucagon itself, it is derived from the proglucagon peptide encoded by the GCG gene. GLP2 stimulates intestinal growth and upregulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. Moreover, GLP2 prevents intestinal hypoplasia resulting from total parenteral nutrition. GLP2R, a G protein-coupled receptor superfamily member is expressed in the gut and closely related to the glucagon receptor (GCGR) and the receptor for GLP1 (GLP1R).
Alias Symbols: -
Protein Interaction Partner: UBC, GCG, CALM1,
Protein Size: 553

Molekulargewicht: 61 kDa

Gen-ID: 9340

NCBI Accession: NM_004246, NP_004237

UniProt: O95838

Pathways: Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Feeding Behaviour