KDM2A Antikörper (Middle Region)
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- Target Alle KDM2A Antikörper anzeigen
- KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Hund, Schwein, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser KDM2A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- LTPPADKPGQ DNRSKLRNMT DFRLAGLDIT DATLRLIIRH MPLLSRLDLS
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against KDM2A. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of Human KDM2A
- Top Product
- Discover our top product KDM2A Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeat freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- KDM2A (Lysine (K)-Specific Demethylase 2A (KDM2A))
- Andere Bezeichnung
- KDM2A (KDM2A Produkte)
- Synonyme
- FBXL11 antikoerper, JHDM1A antikoerper, 100043628 antikoerper, 5530401A10Rik antikoerper, AA589516 antikoerper, AW536790 antikoerper, Cxxc8 antikoerper, Fbl11 antikoerper, Fbl7 antikoerper, Fbxl11 antikoerper, Gm4560 antikoerper, Jhdm1 antikoerper, Jhdm1a antikoerper, lalina antikoerper, KDM2A antikoerper, CXXC8 antikoerper, FBL11 antikoerper, FBL7 antikoerper, LILINA antikoerper, fb76b11 antikoerper, wu:fb76b11 antikoerper, wu:fj11c04 antikoerper, zgc:158441 antikoerper, zgc:158606 antikoerper, lysine demethylase 2A antikoerper, lysine (K)-specific demethylase 2A antikoerper, lysine (K)-specific demethylase 2Aa antikoerper, KDM2A antikoerper, Kdm2a antikoerper, kdm2aa antikoerper
- Hintergrund
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This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least six highly degenerated leucine-rich repeats. This family member plays a role in epigenetic silencing. It nucleates at CpG islands and specifically demethylates both mono- and di-methylated lysine-36 of histone H3.
Alias Symbols: CXXC8, FBL11, FBL7, FBXL11, JHDM1A, LILINA
Protein Interaction Partner: RB1, E2F1, EED, SKP1, MPG, ZNF512B, UBE2G2, SMAD7, SMAD3, HIST3H3, HIST2H3C, KIAA0368, ELAVL1, UBC, BCL6, FOS, RELA,
Protein Size: 620 - Molekulargewicht
- 68 kDa
- Gen-ID
- 22992
- NCBI Accession
- NM_012308, NP_036440
- Pathways
- Warburg Effekt
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