PRKRIR Antikörper (N-Term)

Produktnummer ABIN2786788

Produktdetails anti-PRKRIR Antikörper

Target: PRKRIR (Protein-Kinase, Interferon-Inducible Double Stranded RNA Dependent Inhibitor, Repressor of (p58 Repressor) (PRKRIR))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Pferd, Kaninchen, Rind (Kuh), Meerschweinchen, Hund, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRKRIR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VENCRRADLE DKTPDQLNKH YRLCAKHFET SMICRTSPYR TVLRDNAIPT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against PRKRIR. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PRKRIR

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 761 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PRKRIR

Target: PRKRIR (Protein-Kinase, Interferon-Inducible Double Stranded RNA Dependent Inhibitor, Repressor of (p58 Repressor) (PRKRIR))

Andere Bezeichnung: PRKRIR (PRKRIR Produkte)

Synonyme: DAP4 antikoerper, P52rIPK antikoerper, THAP0 antikoerper, THAP12 antikoerper, 2900052B10Rik antikoerper, Dap4 antikoerper, Rpkrir antikoerper, dap4 antikoerper, p52ripk antikoerper, MGC75860 antikoerper, PRKRIR antikoerper, prkrir antikoerper, prkrir.S antikoerper, THAP domain containing 12 antikoerper, THAP domain containing 12 S homeolog antikoerper, THAP12 antikoerper, Thap12 antikoerper, thap12 antikoerper, thap12.S antikoerper

Hintergrund: PRKRIR is upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). PRKRIR may block the PKR-inhibitory function of P58IPK, resulting in restoration of kinase activity and suppression of cell growth.
Alias Symbols: DAP4, MGC102750, P52rIPK, THAP0
Protein Interaction Partner: TACC1, PASK, STK4, STK3, UBC, DDX58, PRKRIR, EIF2S1, DNAJC3, EIF2AK2, TP53,
Protein Size: 761

Molekulargewicht: 88 kDa

Gen-ID: 5612

NCBI Accession: NM_004705, NP_004696

UniProt: O43422