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MVK Antikörper (Middle Region)

MVK Reaktivität: Human, Maus, Ratte, Meerschweinchen, Pferd, Rind (Kuh), Hund, Kaninchen, Zebrafisch (Danio rerio), Schwein, Ziege, Saccharomyces cerevisiae WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2786519
  • Target Alle MVK Antikörper anzeigen
    MVK (Mevalonate Kinase (MVK))
    Bindungsspezifität
    • 10
    • 8
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    Human, Maus, Ratte, Meerschweinchen, Pferd, Rind (Kuh), Hund, Kaninchen, Zebrafisch (Danio rerio), Schwein, Ziege, Saccharomyces cerevisiae
    Wirt
    • 44
    • 4
    Kaninchen
    Klonalität
    • 46
    • 2
    Polyklonal
    Konjugat
    • 26
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MVK Antikörper ist unkonjugiert
    Applikation
    • 35
    • 22
    • 11
    • 10
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    KEDLELINKW AFQGERMIHG NPSGVDNAVS TWGGALRYHQ GKISSLKRSP
    Homologie
    Cow: 100%, Dog: 86%, Goat: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 93%, Zebrafish: 93%
    Produktmerkmale
    This is a rabbit polyclonal antibody against MVK. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human MVK
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    Discover our top product MVK Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 396 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    MVK (Mevalonate Kinase (MVK))
    Andere Bezeichnung
    MVK (MVK Produkte)
    Synonyme
    F21A20.160 antikoerper, F21A20_160 antikoerper, MEVALONATE KINASE antikoerper, MVK antikoerper, mevalonate kinase antikoerper, DDBDRAFT_0168621 antikoerper, DDBDRAFT_0302479 antikoerper, DDB_0168621 antikoerper, DDB_0302479 antikoerper, LRBP antikoerper, MK antikoerper, MVLK antikoerper, POROK3 antikoerper, 2310010A05Rik antikoerper, AI256848 antikoerper, AI414037 antikoerper, zgc:103473 antikoerper, mevalonate kinase antikoerper, mvk antikoerper, hypothetical protein antikoerper, MVK antikoerper, MK antikoerper, MA_RS03165 antikoerper, PAB_RS02890 antikoerper, LMOf2365_0011 antikoerper, mvk antikoerper, RCI_RS14145 antikoerper, TGAM_RS08735 antikoerper, MMAH_RS07705 antikoerper, TAGG_RS01605 antikoerper, SHELL_RS02965 antikoerper, MVOL_RS03085 antikoerper, Igag_1464 antikoerper, VDIS_RS11260 antikoerper, MFER_RS04560 antikoerper, DESMU_RS01555 antikoerper, ARCVE_RS02955 antikoerper, MZHIL_RS05110 antikoerper, Mvk antikoerper
    Hintergrund
    MVK is the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash.This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Two transcript variants that encode the same protein have been found for this gene.
    Alias Symbols: LRBP, MVLK, MK
    Protein Interaction Partner: MVK, PPP1CB, GSS, MAT1A, POT1, TERF1, UBC, EWSR1,
    Protein Size: 396
    Molekulargewicht
    42 kDa
    Gen-ID
    4598
    NCBI Accession
    NM_000431, NP_000422
    UniProt
    Q03426
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