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FBXO33 Antikörper (Middle Region)

FBXO33 Reaktivität: Ratte, Human, Maus, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Pferd, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2786447
  • Target Alle FBXO33 Antikörper anzeigen
    FBXO33 (F-Box Protein 33 (FBXO33))
    Bindungsspezifität
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    Ratte, Human, Maus, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Pferd, Zebrafisch (Danio rerio)
    Wirt
    • 20
    • 3
    Kaninchen
    Klonalität
    • 23
    Polyklonal
    Konjugat
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FBXO33 Antikörper ist unkonjugiert
    Applikation
    • 13
    • 13
    • 7
    • 5
    • 3
    • 3
    Western Blotting (WB)
    Sequenz
    VIDTSGFPDL SDNRNEDPLV LLAWRCTKLS LLAIHGYTVW AHNLIAIARL
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
    Produktmerkmale
    This is a rabbit polyclonal antibody against FBXO33. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human FBXO33
    Top Product
    Discover our top product FBXO33 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 555 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    FBXO33 (F-Box Protein 33 (FBXO33))
    Andere Bezeichnung
    FBXO33 (FBXO33 Produkte)
    Synonyme
    FBXO33 antikoerper, BMND12 antikoerper, Fbx33 antikoerper, c14_5247 antikoerper, 5730501N20Rik antikoerper, AI642135 antikoerper, F-box protein 33 antikoerper, F-box protein 33 S homeolog antikoerper, FBXO33 antikoerper, fbxo33 antikoerper, fbxo33.S antikoerper, Fbxo33 antikoerper
    Hintergrund
    FBXO33 is the substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. FBXO33 probably recognizes and binds to phosphorylated target proteins. Recognizes YBX1.Members of the F-box protein family, such as FBXO33, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].
    Alias Symbols: Fbx33, c14_5247, BMND12
    Protein Interaction Partner: CUL1, YBX1, UBC,
    Protein Size: 555
    Molekulargewicht
    62 kDa
    Gen-ID
    254170
    NCBI Accession
    NM_203301, NP_976046
    UniProt
    Q7Z6M2
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