APBB2 Antikörper (Middle Region)

Produktnummer ABIN2786292

Produktdetails anti-APBB2 Antikörper

Target: APBB2 (Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 2 (APBB2))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Hund, Pferd, Kaninchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser APBB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: QNLAPSDEES SWTTLSQDSA SPSSPDETDI WSDHSFQTDP DLPPGWKRVS

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against APBB2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human APBB2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 736 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-APBB2 Antikörper (ABIN2786292)

Hong, Hsu, Schultz, Pratt, Mattison, Chang: "Zfra affects TNF-mediated cell death by interacting with death domain protein TRADD and negatively regulates the activation of NF-kappaB, JNK1, p53 and WOX1 during stress response." in: BMC molecular biology, Vol. 8, pp. 50, (2007) (PubMed).

Details zu APBB2

Target: APBB2 (Amyloid beta (A4) Precursor Protein-Binding, Family B, Member 2 (APBB2))

Andere Bezeichnung: APBB2 (APBB2 Produkte)

Synonyme: FE65L antikoerper, FE65L1 antikoerper, 2310007D03Rik antikoerper, Rirl1 antikoerper, TR2L antikoerper, Zfra antikoerper, RGD1562438 antikoerper, APBB2 antikoerper, fe65l antikoerper, fe65l1 antikoerper, DKFZp469I236 antikoerper, si:ch211-201g8.2 antikoerper, amyloid beta precursor protein binding family B member 2 antikoerper, amyloid beta (A4) precursor protein-binding, family B, member 2 antikoerper, amyloid beta (A4) precursor protein-binding, family B, member 2b antikoerper, APBB2 antikoerper, Apbb2 antikoerper, apbb2 antikoerper, apbb2b antikoerper

Hintergrund: APBB2 may modulate the internalization of beta-amyloid precursor protein.The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction.
Alias Symbols: FE65L, FE65L1, MGC35575
Protein Interaction Partner: UBC, EGFR, SMURF1, SMAD4, APLP2, APP,
Protein Size: 736

Molekulargewicht: 81 kDa

Gen-ID: 323

NCBI Accession: NM_173075, NP_775098

UniProt: Q92870