GNAO1 Antikörper (Middle Region)

Produktnummer ABIN2786202

Produktdetails anti-GNAO1 Antikörper

Target: GNAO1 (Guanine Nucleotide Binding Protein (G Protein), alpha Activating Activity Polypeptide O (GNAO1))

Bindungsspezifität: Middle Region

Reaktivität: Maus, Human, Ratte, Kaninchen, Rind (Kuh), Hund, Pferd, Meerschweinchen, Schaf, Zebrafisch (Danio rerio), Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GNAO1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: CDVVSRMEDT EPFSAELLSA MMRLWGDSGI QECFNRSREY QLNDSAKYYL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against GNAO1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GNAO1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 354 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-GNAO1 Antikörper (ABIN2786202)

Zupancic, Blejec, Herman, Veber, Verbovsek, Korsic, Knezevic, Rozman, Turnsek, Gruden, Motaln: "Identification of plasma biomarker candidates in glioblastoma using an antibody-array-based proteomic approach." in: Radiology and oncology, Vol. 48, Issue 3, pp. 257-66, (2014) (PubMed).

Details zu GNAO1

Target: GNAO1 (Guanine Nucleotide Binding Protein (G Protein), alpha Activating Activity Polypeptide O (GNAO1))

Andere Bezeichnung: GNAO1 (GNAO1 Produkte)

Synonyme: G-ALPHA-o antikoerper, GNAO antikoerper, AW050213 antikoerper, Galphao antikoerper, Gnao antikoerper, alphaO antikoerper, gnao1 antikoerper, wu:fq26h05 antikoerper, zgc:73315 antikoerper, RATBPGTPC antikoerper, XGalpha01 antikoerper, gnao1-A antikoerper, zgc:73153 antikoerper, G protein subunit alpha o1 antikoerper, guanine nucleotide binding protein, alpha O antikoerper, guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a antikoerper, G protein subunit alpha o1 L homeolog antikoerper, Guanine nucleotide-binding protein G(o) subunit alpha antikoerper, guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, b antikoerper, GNAO1 antikoerper, Gnao1 antikoerper, gnao1a antikoerper, gnao1.L antikoerper, goa-1 antikoerper, gnao1b antikoerper

Hintergrund: Activated Goalpha interacted directly with PLZF, and enhanced its function as a transcriptional and cell growth suppressor. Goalpha might play a role in mediating extracellular signal-regulated kinase activation by G protein-coupled receptors in the brain.
Alias Symbols: DKFZp686O0962, G-ALPHA-o, GNAO
Protein Interaction Partner: UBC, ADRA2A, BAG3, Htt, RGS9, GABBR1, Haus4, RGS1, RIC8A, DCTN2, KLHL3, SCN8A, PDE6G, CRHR1, GPSM2, HRH4, NGB, S1PR5, RGS19, GRM6, FFAR2, TSHR, RGS5, RGS10, RGS7, RGS4, RGS16, RGS14, PTPRU, CCR5, NUCB1, PDE6H, CACNA1B, OPRM1, OPRD1, GNAO1, GNAI1, ADRA2C,
Protein Size: 354

Molekulargewicht: 40 kDa

Gen-ID: 2775

NCBI Accession: NM_138736, NP_620073

UniProt: B3KP89

Pathways: G-protein mediated Events