POLL Antikörper (Middle Region)

Produktnummer ABIN2785955

Produktdetails anti-POLL Antikörper

Target: POLL (Polymerase (DNA Directed), lambda (POLL))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus, Kaninchen, Rind (Kuh), Meerschweinchen, Hund, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POLL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SLSEHALSTA VVRNTHGCKV GPGRVLPTPT EKDVFRLLGL PYREPAERDW

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 93%, Yeast: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against POLL. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human POLL

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 575 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu POLL

Target: POLL (Polymerase (DNA Directed), lambda (POLL))

Andere Bezeichnung: POLL (POLL Produkte)

Synonyme: T10O24.13 antikoerper, T10O24_13 antikoerper, zgc:66320 antikoerper, zgc:77901 antikoerper, wu:fe49a04 antikoerper, beta-n antikoerper, pol-kappa antikoerper, BETAN antikoerper, POLKAPPA antikoerper, 1110003P06Rik antikoerper, AV007317 antikoerper, DNA polymerase lambda (POLL) antikoerper, DNA polymerase lambda antikoerper, polymerase (DNA directed), lambda antikoerper, polymerase (DNA) lambda antikoerper, Pol{lambda} antikoerper, PTRG_00468 antikoerper, poll antikoerper, POLL antikoerper, MCYG_03796 antikoerper, LOC9325878 antikoerper, MGYG_02138 antikoerper, Poll antikoerper

Hintergrund: POLL is a repair polymerase.It is involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Has both DNA polymerase and terminal transferase activities. Has a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
Alias Symbols: BETA-N, FLJ46002, POL-KAPPA, BETAN, POLKAPPA
Protein Interaction Partner: KRTAP10-3, KRTAP10-7, FAM9B, KRT40, FSD2, SSX2IP, TFIP11, PNMA1, TFCP2, MAGEA12, TRIM23, APP, DCUN1D1, REV1, LDOC1, RPA1, PCNA, CDK2, UBE2H, UBE2E1, UBE2D3, UBE2D2, UBE2D1,
Protein Size: 575

Molekulargewicht: 63 kDa

Gen-ID: 27343

NCBI Accession: NM_013274, NP_037406

UniProt: Q9UGP5

Pathways: DNA Reparatur, Production of Molecular Mediator of Immune Response