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Lactate Dehydrogenase A Antikörper (Middle Region)

LDHA Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Pferd, Hund, Meerschweinchen, Ziege, Zebrafisch (Danio rerio) WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2785876
  • Target Alle Lactate Dehydrogenase A (LDHA) Antikörper anzeigen
    Lactate Dehydrogenase A (LDHA)
    Bindungsspezifität
    • 13
    • 9
    • 8
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 83
    • 42
    • 32
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Kaninchen, Rind (Kuh), Pferd, Hund, Meerschweinchen, Ziege, Zebrafisch (Danio rerio)
    Wirt
    • 94
    • 18
    • 5
    • 2
    Kaninchen
    Klonalität
    • 100
    • 17
    Polyklonal
    Konjugat
    • 51
    • 20
    • 14
    • 8
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    Dieser Lactate Dehydrogenase A Antikörper ist unkonjugiert
    Applikation
    • 81
    • 48
    • 42
    • 27
    • 14
    • 14
    • 11
    • 9
    • 6
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    PLSCHGWVLG EHGDSSVPVW SGMNVAGVSL KTLHPDLGTD KDKEQWKEVH
    Homologie
    Cow: 79%, Dog: 86%, Goat: 79%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 79%, Zebrafish: 92%
    Produktmerkmale
    This is a rabbit polyclonal antibody against LDHA. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human LDHA
    Top Product
    Discover our top product LDHA Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 332 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Listerman, Bledau, Grishina, Neugebauer: "Extragenic accumulation of RNA polymerase II enhances transcription by RNA polymerase III." in: PLoS genetics, Vol. 3, Issue 11, pp. e212, (2008) (PubMed).

  • Target
    Lactate Dehydrogenase A (LDHA)
    Andere Bezeichnung
    LDHA (LDHA Produkte)
    Synonyme
    GSD11 antikoerper, LDH1 antikoerper, LDHM antikoerper, LDH-M antikoerper, ldh-h antikoerper, ldha antikoerper, ldha-B antikoerper, ldhbb antikoerper, trg-5 antikoerper, Ldh1 antikoerper, Ldhm antikoerper, l7R2 antikoerper, gsd11 antikoerper, ldh-m antikoerper, ldh1 antikoerper, ldhm antikoerper, pig19 antikoerper, ldha1 antikoerper, ldhab antikoerper, LDH-A antikoerper, LDHC antikoerper, lactate dehydrogenase A antikoerper, lactate dehydrogenase B L homeolog antikoerper, lactate dehydrogenase A4 antikoerper, lactate dehydrogenase A L homeolog antikoerper, L-lactate dehydrogenase A chain antikoerper, LDHA antikoerper, ldhb.L antikoerper, Ldha antikoerper, ldha antikoerper, ldha.L antikoerper, LOC100713875 antikoerper
    Hintergrund
    LDHA catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria.The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: LDH-M, LDH1, PIG19, LDHM, GSD11
    Protein Interaction Partner: MAPK10, LDHB, FUS, HUWE1, ISG15, UBC, SUMO2, SUMO3, STAU1, RPA3, RPA2, RPA1, ASB9, RNF2, CNDP2, NAGK, C11orf58, NDRG1, BZW1, KYNU, TCEA1, SORD, SMS, RPS6KA1, PGD, PAFAH1B3, GSR, PDIA3, GNAI3, DLD, CSE1L, LDHAL6B, FTO, BCCIP, XRN1, FBXO6, UPF2, YWHAQ, METT
    Protein Size: 332
    Molekulargewicht
    37 kDa
    Gen-ID
    3939
    NCBI Accession
    NM_005566, NP_005557
    UniProt
    P00338
    Pathways
    Warburg Effekt
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