FTH1 Antikörper (Middle Region)

Produktnummer ABIN2785803

Produktdetails anti-FTH1 Antikörper

Target: FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Schaf, Hund, Kaninchen, Pferd, Meerschweinchen, Rind (Kuh), Ziege

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FTH1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: NVNQSLLELH KLATDKNDPH LCDFIETHYL NEQVKAIKEL GDHVTNLRKM

Homologie: Cow: 93%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against FTH1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FTH1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 183 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-FTH1 Antikörper (ABIN2785803)

Potrykus, Stead, Maccallum, Urgast, Raab, van Rooijen, Feldmann, Brown: "Fungal iron availability during deep seated candidiasis is defined by a complex interplay involving systemic and local events." in: PLoS pathogens, Vol. 9, Issue 10, pp. e1003676, (2013) (PubMed).

Details zu FTH1

Target: FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))

Andere Bezeichnung: FTH1 (FTH1 Produkte)

Synonyme: FHC antikoerper, FTH antikoerper, FTHL6 antikoerper, PIG15 antikoerper, PLIF antikoerper, apoferritin antikoerper, ferritin antikoerper, fhc antikoerper, fth antikoerper, fth1 antikoerper, fthl6 antikoerper, ftn-2 antikoerper, pig15 antikoerper, plif antikoerper, fth1b antikoerper, Fth antikoerper, HFt antikoerper, MFH antikoerper, fb06g09 antikoerper, hm:zeh1145 antikoerper, wu:fb06g09 antikoerper, wu:fq18c10 antikoerper, zeh1145 antikoerper, ferritin heavy chain 1 antikoerper, ferritin, heavy polypeptide 1 L homeolog antikoerper, ferritin, heavy polypeptide 1 S homeolog antikoerper, ferritin heavy polypeptide 1 antikoerper, ferritin, heavy polypeptide 1a antikoerper, ferritin antikoerper, ferritin, heavy polypeptide 1 antikoerper, tudor domain containing 9 antikoerper, ferritin, heavy polypeptide 1 a antikoerper, FTH1 antikoerper, fth1.L antikoerper, fth1.S antikoerper, Fth1 antikoerper, fth1a antikoerper, EAMY_RS19690 antikoerper, fth1 antikoerper, TDRD9 antikoerper

Hintergrund: FTH1 is the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FTH, FTHL6, MGC104426, PIG15, PLIF, FHC
Protein Interaction Partner: SDCBP, FTL, FTH1, WDYHV1, CEP57, AURKB, TP53, AURKA, ASB15, ASB16, SUPT16H, SET, MAPK9, MAX, IGSF8, TICAM2, HCVgp1, PIAS4, CDC16, YWHAE, SOX5, MYL3, LBP, KPNA2, GRB2, DAXX, CSNK2B, CDC25A, ATP6V1B1, CD99, SPP1, TRAF4, SUMO2, UBC, Cep55, Trim28, NR1I3, NR3
Protein Size: 183

Molekulargewicht: 21 kDa

Gen-ID: 2495

NCBI Accession: NM_002032, NP_002023

UniProt: P02794

Pathways: Transition Metal Ion Homeostasis