ERCC5 Antikörper (N-Term)
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- Target Alle ERCC5 Antikörper anzeigen
- ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ERCC5 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- NPQAIDIESE DFSSLPPEVK HEILTDMKEF TKRRRTLFEA MPEESDDFSQ
- Homologie
- Cow: 86%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against ERCC5. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human ERCC5
- Top Product
- Discover our top product ERCC5 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 1186 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))
- Andere Bezeichnung
- ERCC5 (ERCC5 Produkte)
- Synonyme
- COFS3 antikoerper, ERCM2 antikoerper, UVDR antikoerper, XPG antikoerper, XPGC antikoerper, cofs3 antikoerper, ercm2 antikoerper, uvdr antikoerper, xpg antikoerper, xpgc antikoerper, Xpg antikoerper, ERCC excision repair 5, endonuclease antikoerper, excision repair cross-complementation group 5 L homeolog antikoerper, excision repair cross-complementing rodent repair deficiency, complementation group 5 antikoerper, ERCC5 antikoerper, ercc5.L antikoerper, Ercc5 antikoerper
- Hintergrund
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Excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G) is involved in excision repair of UV-induced DNA damage. Mutations cause Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Excision repair cross-complementing rodent repair deficiency, complementation group 5 (xeroderma pigmentosum, complementation group G) is involved in excision repair of UV-induced DNA damage. Mutations cause Cockayne syndrome, which is characterized by severe growth defects, mental retardation, and cachexia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been described, but the biological validity of all variants has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: COFS3, ERCM2, UVDR, XPG, XPGC
Protein Interaction Partner: UBC, CDK7, GTF2H1, POLR2A, EWSR1, ERCC6, SUMO2, PIDD1, BCL6, TAF10, ERCC3, NTHL1, GTF2H4, PCNA, ERCC2,
Protein Size: 1186 - Molekulargewicht
- 133 kDa
- Gen-ID
- 2073
- NCBI Accession
- NM_000123, NP_000114
- UniProt
- P28715
- Pathways
- DNA Reparatur
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