HSD17B3 Antikörper (N-Term)

Produktnummer ABIN2785439

Produktdetails anti-HSD17B3 Antikörper

Target: HSD17B3 (Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSD17B3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AVITGAGDGI GKAYSFELAK RGLNVVLISR TLEKLEAIAT EIERTTGRSV

Homologie: Horse: 79%, Human: 100%, Rat: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against HSD17B3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 310 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-HSD17B3 Antikörper (ABIN2785439)

Bertin, Dury, Ouellet, Pelletier, Labrie: "Localization of the androgen-synthesizing enzymes, androgen receptor, and sex steroids in the vagina: possible implications for the treatment of postmenopausal sexual dysfunction." in: The journal of sexual medicine, Vol. 11, Issue 8, pp. 1949-61, (2014) (PubMed).

Details zu HSD17B3

Target: HSD17B3 (Hydroxysteroid (17-Beta) Dehydrogenase 3 (HSD17B3))

Andere Bezeichnung: HSD17B3 (HSD17B3 Produkte)

Synonyme: EDH17B3 antikoerper, SDR12C2 antikoerper, hydroxysteroid (17-beta) dehydrogenase 3 antikoerper, hydroxysteroid 17-beta dehydrogenase 3 antikoerper, Hsd17b3 antikoerper, HSD17B3 antikoerper

Hintergrund: This isoform of 17 beta-hydroxysteroid dehydrogenase is expressed predominantly in the testis and catalyzes the conversion of androstenedione to testosterone. It preferentially uses NADP as cofactor. Deficiency can result in male pseudohermaphroditism with gynecomastia.
Alias Symbols: EDH17B3, SDR12C2
Protein Size: 310

Molekulargewicht: 34 kDa

Gen-ID: 3293

NCBI Accession: NM_000197, NP_000188

UniProt: P37058

Pathways: Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis