Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

COPS8 Antikörper (Middle Region)

COPS8 Reaktivität: Human, Ratte, Maus, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Hund WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2784840
  • Target Alle COPS8 Antikörper anzeigen
    COPS8 (COP9 Signalosome Subunit 8 (COPS8))
    Bindungsspezifität
    • 15
    • 9
    • 5
    • 4
    • 4
    • 2
    • 1
    Middle Region
    Reaktivität
    • 48
    • 22
    • 21
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Ratte, Maus, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Hund
    Wirt
    • 43
    • 5
    Kaninchen
    Klonalität
    • 46
    • 2
    Polyklonal
    Konjugat
    • 20
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser COPS8 Antikörper ist unkonjugiert
    Applikation
    • 42
    • 20
    • 13
    • 6
    • 5
    • 4
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    TRMVLPRKPV AGALDVSFNK FIPLSEPAPV PPIPNEQQLA RLTDYVAFLE
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against COPS8. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human COPS8
    Top Product
    Discover our top product COPS8 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 209 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Pick, Golan, Zimbler, Guo, Sharaby, Tsuge, Hofmann, Wei: "The minimal deneddylase core of the COP9 signalosome excludes the Csn6 MPN- domain." in: PLoS ONE, Vol. 7, Issue 8, pp. e43980, (2012) (PubMed).

  • Target
    COPS8 (COP9 Signalosome Subunit 8 (COPS8))
    Andere Bezeichnung
    COPS8 (COPS8 Produkte)
    Synonyme
    COP9 antikoerper, CSN8 antikoerper, SGN8 antikoerper, csn8 antikoerper, cops8 antikoerper, MGC76051 antikoerper, MGC80215 antikoerper, DDBDRAFT_0167123 antikoerper, DDBDRAFT_0233107 antikoerper, DDB_0167123 antikoerper, DDB_0233107 antikoerper, zgc:56319 antikoerper, zgc:86840 antikoerper, MGC86182 antikoerper, 9430009J09Rik antikoerper, AA408242 antikoerper, Csn8 antikoerper, Sgn8 antikoerper, CONSTITUTIVE PHOTOMORPHOGENIC 9 antikoerper, COP9 SIGNALOSOME SUBUNIT 8 antikoerper, DL3095C antikoerper, EMB143 antikoerper, EMBRYO DEFECTIVE 143 antikoerper, FCAALL.131 antikoerper, FUS7 antikoerper, FUSCA 7 antikoerper, FUSCA PROTEIN FUS7 antikoerper, CG13383 antikoerper, CG33297 antikoerper, CG42522 antikoerper, CH8 antikoerper, Dch8 antikoerper, Dmel\\CG42522 antikoerper, Dmel_CG13383 antikoerper, l(2)SH1829 antikoerper, l(2)SH2 1829 antikoerper, COP9 signalosome subunit 8 antikoerper, COP9 signalosome subunit 8 S homeolog antikoerper, COP9 signalosome complex subunit 8 antikoerper, COP9 signalosome subunit 8 L homeolog antikoerper, COP9 signalosome, subunit CSN8 antikoerper, COPS8 antikoerper, Cops8 antikoerper, cops8 antikoerper, cops8.S antikoerper, CSN8 antikoerper, csn8 antikoerper, cops8.L antikoerper, COP9 antikoerper
    Hintergrund
    The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
    Alias Symbols: COP9, CSN8, MGC1297, MGC43256, SGN8
    Protein Interaction Partner: USHBP1, GPS1, cul1, WDR77, SRRT, COPS7A, VIM, COPS4, FBXO6, FBXW4, COPS5, vpr, IRF5, DDIT3, COPS2, COPS3, COPS6, PINK1, RFWD2, CUL4A, UBC, LRR1, DDA1, DDB2, DCUN1D1, VPRBP, CUL2, CUL3, CUL4B, CUL5, NEDD8, JUN, GFER, ERCC8, DDB1, CTNNB1, RAE1, COPS8, EIF3E
    Protein Size: 209
    Molekulargewicht
    23 kDa
    Gen-ID
    10920
    NCBI Accession
    NM_006710, NP_006701
    UniProt
    Q99627
    Pathways
    Zellzyklus
Sie sind hier:
Kundenservice