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TdT Antikörper (N-Term)

DNTT Reaktivität: Human, Maus, Ratte, Pferd, Hund, Rind (Kuh), Meerschweinchen, Schwein, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2784740
  • Target Alle TdT (DNTT) Antikörper anzeigen
    TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))
    Bindungsspezifität
    • 16
    • 9
    • 8
    • 8
    • 6
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 87
    • 18
    • 16
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Pferd, Hund, Rind (Kuh), Meerschweinchen, Schwein, Kaninchen
    Wirt
    • 73
    • 14
    Kaninchen
    Klonalität
    • 69
    • 18
    Polyklonal
    Konjugat
    • 42
    • 8
    • 7
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser TdT Antikörper ist unkonjugiert
    Applikation
    • 53
    • 44
    • 10
    • 9
    • 8
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    FQDLVVFILE KKMGTTRRAF LMELARRKGF RVENELSDSV THIVAENNSG
    Homologie
    Cow: 100%, Dog: 79%, Guinea Pig: 82%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against DNTT. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human DNTT
    Top Product
    Discover our top product DNTT Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 509 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    TdT (DNTT) (Deoxynucleotidyltransferase, terminal (DNTT))
    Andere Bezeichnung
    DNTT (DNTT Produkte)
    Synonyme
    TdT antikoerper, TDT antikoerper, BB160593 antikoerper, Tdt antikoerper, dntt-A antikoerper, dntt antikoerper, DNA nucleotidylexotransferase antikoerper, deoxynucleotidyltransferase, terminal antikoerper, DNA nucleotidylexotransferase L homeolog antikoerper, terminal deoxynucleotidyl transferase antikoerper, DNTT antikoerper, dntt antikoerper, Dntt antikoerper, dntt.L antikoerper, tdt antikoerper
    Hintergrund
    DNTT is a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, DNTT is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. This gene is a member of the DNA polymerase type-X family and encodes a template-independent DNA polymerase that catalyzes the addition of deoxynucleotides to the 3'-hydroxyl terminus of oligonucleotide primers. In vivo, the encoded protein is expressed in a restricted population of normal and malignant pre-B and pre-T lymphocytes during early differentiation, where it generates antigen receptor diversity by synthesizing non-germ line elements (N-regions) at the junctions of rearranged Ig heavy chain and T cell receptor gene segments. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
    Alias Symbols: TDT
    Protein Interaction Partner: REL, APOA1, DNTTIP1, UBC, PRPF19, DNTTIP2, PCNA, XRCC6, ABTB2, CUL3,
    Protein Size: 509
    Molekulargewicht
    58 kDa
    Gen-ID
    1791
    NCBI Accession
    NM_004088, NP_004079
    UniProt
    P04053
    Pathways
    DNA Reparatur
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