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CYP1B1 Antikörper (Middle Region)

CYP1B1 Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2784612
  • Target Alle CYP1B1 Antikörper anzeigen
    CYP1B1 (Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1))
    Bindungsspezifität
    • 15
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 44
    • 32
    • 16
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd
    Wirt
    • 57
    • 2
    Kaninchen
    Klonalität
    • 56
    • 3
    Polyklonal
    Konjugat
    • 26
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CYP1B1 Antikörper ist unkonjugiert
    Applikation
    • 41
    • 14
    • 10
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    Western Blotting (WB)
    Sequenz
    AVANVMSAVC FGCRYSHDDP EFRELLSHNE EFGRTVGAGS LVDVMPWLQY
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against CYP1B1. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human CYP1B1
    Top Product
    Discover our top product CYP1B1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 543 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Staršíchová, Hrubá, Slabáková, Pernicová, Procházková, P?n?íková, Seda, Kabátková, Vondrá?ek, Kozubík, Machala, Sou?ek: "TGF-?1 signaling plays a dominant role in the crosstalk between TGF-?1 and the aryl hydrocarbon receptor ligand in prostate epithelial cells." in: Cellular signalling, Vol. 24, Issue 8, pp. 1665-76, (2012) (PubMed).

    Wang, Hawkins, Miller: "Aryl hydrocarbon receptor-mediated up-regulation of ATP-driven xenobiotic efflux transporters at the blood-brain barrier." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 25, Issue 2, pp. 644-52, (2011) (PubMed).

  • Target
    CYP1B1 (Cytochrome P450, Family 1, Subfamily B, Polypeptide 1 (CYP1B1))
    Andere Bezeichnung
    CYP1B1 (CYP1B1 Produkte)
    Synonyme
    CP1B antikoerper, CYPIB1 antikoerper, GLC3A antikoerper, P4501B1 antikoerper, P4501b1 antikoerper, CYP1B1 antikoerper, CYP1B antikoerper, zgc:136223 antikoerper, cytochrome P450 family 1 subfamily B member 1 antikoerper, cytochrome P450, family 1, subfamily b, polypeptide 1 antikoerper, cytochrome P450, family 1, subfamily B, polypeptide 1 antikoerper, cytochrome P450 1B1 antikoerper, CYP1B1 antikoerper, Cyp1b1 antikoerper, cyp1b1 antikoerper, LOC100719054 antikoerper
    Hintergrund
    CYP1B1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP1B1 localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma, therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma, therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: CP1B, GLC3A, P4501B1, CYPIB1
    Protein Interaction Partner: UBC, SAE1,
    Protein Size: 543
    Molekulargewicht
    61 kDa
    Gen-ID
    1545
    NCBI Accession
    NM_000104, NP_000095
    UniProt
    Q16678
    Pathways
    Steroid Hormone Biosynthesis
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