CYP3A4 Antikörper (Middle Region)
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- Target Alle CYP3A4 Antikörper anzeigen
- CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Schaf, Ziege, Pferd
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CYP3A4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- MIPSYALHRD PKYWTEPEKF LPERFSKKNK DNIDPYIYTP FGSGPRNCIG
- Homologie
- Cow: 86%, Dog: 85%, Goat: 86%, Guinea Pig: 93%, Horse: 92%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%, Sheep: 86%
- Produktmerkmale
- This is a rabbit polyclonal antibody against CYP3A4. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human CYP3A4
- Top Product
- Discover our top product CYP3A4 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 503 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Identification and characterization of a defective CYP3A4 genotype in a kidney transplant patient with severely diminished tacrolimus clearance." in: Clinical pharmacology and therapeutics, Vol. 95, Issue 4, pp. 416-22, (2014) (PubMed).
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Identification and characterization of a defective CYP3A4 genotype in a kidney transplant patient with severely diminished tacrolimus clearance." in: Clinical pharmacology and therapeutics, Vol. 95, Issue 4, pp. 416-22, (2014) (PubMed).
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- Target
- CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))
- Andere Bezeichnung
- CYP3A4 (CYP3A4 Produkte)
- Synonyme
- CP33 antikoerper, CP34 antikoerper, CYP3A antikoerper, CYP3A3 antikoerper, CYPIIIA3 antikoerper, CYPIIIA4 antikoerper, HLP antikoerper, NF-25 antikoerper, P450C3 antikoerper, P450PCN1 antikoerper, MGC108372 antikoerper, CYP3A80 antikoerper, CYP3A4 antikoerper, CYP3A21 antikoerper, CYPIIIA21 antikoerper, CYP3A12 antikoerper, cytochrome P450 family 3 subfamily A member 4 antikoerper, cytochrome P450 family 3 subfamily A member 43 antikoerper, cytochrome P450 3A4 antikoerper, cytochrome P450, subfamily IIIA, polypeptide 4 antikoerper, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4 antikoerper, cytochrome P450, family 3, subfamily A, polypeptide 4 antikoerper, CYP3A4 antikoerper, CYP3A43 antikoerper, PTRG_01782 antikoerper, PTRG_06060 antikoerper, cyp3a4 antikoerper
- Hintergrund
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This gene, CYP3A4, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This prot
Alias Symbols: CP33, CP34, CYP3A, CYP3A3, HLP, MGC126680, NF-25, P450C3, P450PCN1, CYPIIIA3, CYPIIIA4
Protein Interaction Partner: UBC, PRKCA, PRKACA, PGRMC1, POR, GK, CYB5A, STUB1, AMFR, UGT2B7,
Protein Size: 503 - Molekulargewicht
- 57 kDa
- Gen-ID
- 1576
- NCBI Accession
- NM_017460, NP_059488
- UniProt
- P08684
- Pathways
- Steroid Hormone Biosynthesis
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