NAGS Antikörper (C-Term)

Produktnummer ABIN2784450

Produktdetails anti-NAGS Antikörper

Target: NAGS (N-Acetylglutamate Synthase (NAGS))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Schwein, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NAGS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: YLDKFVVSSS RQGQGSGQML WECLRRDLQT LFWRSRVTNP INPWYFKHSD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against NAGS. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NAGS

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 534 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NAGS

Target: NAGS (N-Acetylglutamate Synthase (NAGS))

Andere Bezeichnung: NAGS (NAGS Produkte)

Synonyme: VF0585 antikoerper, AGAS antikoerper, ARGA antikoerper, 1700120E20Rik antikoerper, argA antikoerper, RGD1565783 antikoerper, N-acetylglutamate synthase antikoerper, amino-acid acetyltransferase ArgA antikoerper, argA antikoerper, ECs3675 antikoerper, VP2371 antikoerper, Psyr_0254 antikoerper, Sde_0360 antikoerper, NAGS antikoerper, Nags antikoerper

Hintergrund: NAGS is a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and, thereby, CPSI activity. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.
Alias Symbols: AGAS, ARGA, MGC133025
Protein Interaction Partner: TMEM39B,
Protein Size: 534

Molekulargewicht: 58 kDa

Gen-ID: 162417

NCBI Accession: NM_153006, NP_694551

UniProt: Q8N159