MDFIC Antikörper (N-Term)

Produktnummer ABIN2784369

Produktdetails anti-MDFIC Antikörper

Target: MDFIC (MyoD Family Inhibitor Domain Containing (MDFIC))

Bindungsspezifität: N-Term

Reaktivität: Human, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MDFIC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SVRPAGRRAR RQRRGAGSAE RPMSGAGEAL APGPVGPQRV AEAGGGQLGS

Homologie: Human: 100%, Rabbit: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against MDFIC. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MDFIC

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 355 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MDFIC

Target: MDFIC (MyoD Family Inhibitor Domain Containing (MDFIC))

Andere Bezeichnung: MDFIC (MDFIC Produkte)

Synonyme: HIC antikoerper, Kdt1 antikoerper, Mdfid antikoerper, MyoD family inhibitor domain containing antikoerper, MyoD family inhibitor domain containing S homeolog antikoerper, MDFIC antikoerper, Mdfic antikoerper, mdfic.S antikoerper

Hintergrund: MDFIC is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain, which is involved in transcriptional regulation of viral genome expression. Alternative translation initiation from an upstream non-AUG (GUG), and an in-frame, downstream AUG codon, results in the production of two isoforms, p40 and p32, respectively, which have different subcellular localization, p32 is mainly found in the cytoplasm, whereas p40 is targeted to the nucleolus. Both isoforms have transcriptional regulatory activity that is attributable to the cysteine-rich C-terminal domain.This gene product is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain, which is involved in transcriptional regulation of viral genome expression. Alternative translation initiation from an upstream non-AUG (GUG), and an in-frame, downstream AUG codon, results in the production of two isoforms, p40 and p32, respectively, which have different subcellular localization, p32 is mainly found in the cytoplasm, whereas p40 is targeted to the nucleolus. Both isoforms have transcriptional regulatory activity that is attributable to the cysteine-rich C-terminal domain.
Alias Symbols: HIC
Protein Interaction Partner: SOCS4, tat, RPS6KA5, CSNK2A1, MDFIC, CDK9, CCNT1,
Protein Size: 355

Molekulargewicht: 37 kDa

Gen-ID: 29969

NCBI Accession: NM_199072, NP_951038

UniProt: Q9P1T7