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PCDHGC4 Antikörper (N-Term)

PCDHGC4 Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Pferd, Schwein, Kaninchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2783728
  • Target Alle PCDHGC4 Antikörper anzeigen
    PCDHGC4 (Protocadherin gamma Subfamily C, 4 (PCDHGC4))
    Bindungsspezifität
    • 8
    • 8
    • 6
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    Human, Maus, Ratte, Zebrafisch (Danio rerio), Pferd, Schwein, Kaninchen
    Wirt
    • 19
    • 1
    Kaninchen
    Klonalität
    • 20
    Polyklonal
    Konjugat
    • 10
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser PCDHGC4 Antikörper ist unkonjugiert
    Applikation
    • 20
    • 15
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    VKKRSDGSLV PELLLEKPLD REKQSDYRLV LTAVDGGNPP RSGTAELRVS
    Homologie
    Horse: 100%, Human: 100%, Mouse: 100%, Pig: 91%, Rabbit: 79%, Rat: 100%, Zebrafish: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against PCDHGC4. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human PCDHGC4
    Top Product
    Discover our top product PCDHGC4 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 938 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    PCDHGC4 (Protocadherin gamma Subfamily C, 4 (PCDHGC4))
    Andere Bezeichnung
    PCDHGC4 (PCDHGC4 Produkte)
    Synonyme
    PCDH-GAMMA-C4 antikoerper, protocadherin gamma c4 antikoerper, protocadherin gamma subfamily C, 4 antikoerper, Pcdhgc4 antikoerper, PCDHGC4 antikoerper
    Hintergrund
    PCDHGC4 is a single-pass type I membrane protein. It contains 6 cadherin domains.PCDHGC4 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
    Alias Symbols: MGC119489, PCDH-GAMMA-C4
    Protein Size: 938
    Molekulargewicht
    98 kDa
    Gen-ID
    56098
    NCBI Accession
    NM_018928, NP_061751
    UniProt
    Q9Y5F7
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