CMAS Antikörper (N-Term)

Produktnummer ABIN2783528

Produktdetails anti-CMAS Antikörper

Target: CMAS (Cytidine Monophosphate N-Acetylneuraminic Acid Synthetase (CMAS))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CMAS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GRGVEKPPHL AALILARGGS KGIPLKNIKH LAGVPLIGWV LRAALDSGAF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CMAS. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CMAS

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 434 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CMAS

Target: CMAS (Cytidine Monophosphate N-Acetylneuraminic Acid Synthetase (CMAS))

Andere Bezeichnung: CMAS (CMAS Produkte)

Synonyme: CSS antikoerper, cmas antikoerper, cmas1 antikoerper, si:dkey-183c2.1 antikoerper, wu:fj16c12 antikoerper, zgc:136241 antikoerper, AW208911 antikoerper, CMPNeu5Ac antikoerper, D6Bwg0250e antikoerper, cytidine monophosphate N-acetylneuraminic acid synthetase antikoerper, cytidine monophosphate N-acetylneuraminic acid synthetase a antikoerper, cytidine monophospho-N-acetylneuraminic acid synthetase antikoerper, CMAS antikoerper, Cmas antikoerper, cmasa antikoerper, cmas antikoerper

Hintergrund: CMAS is an enzyme that catalyzes the activation of Neu5Ac to Cytidine 5-prime-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac), which provides the substrate required for the addition of sialic acid. Sialic acids of cell surface glycoproteins and glycolipids play a pivotal role in the structure and function of animal tissues. The pattern of cell surface sialylation is highly regulated during embryonic development, and changes with stages of differentiation. Studies of a similar murine protein suggest that this protein localizes to the nucleus.The enzyme encoded by this gene catalyzes the activation of Neu5Ac to Cytidine 5-prime-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac), which provides the substrate required for the addition of sialic acid. Sialic acids of cell surface glycoproteins and glycolipids play a pivotal role in the structure and function of animal tissues. The pattern of cell surface sialylation is highly regulated during embryonic development, and changes with stages of differentiation. Studies of a similar murine protein suggest that this protein localizes to the nucleus.
Alias Symbols: CSS
Protein Interaction Partner: SUMO2, SUMO3, UBC, FBXO6, APP, SIGLEC12,
Protein Size: 434

Molekulargewicht: 48 kDa

Gen-ID: 55907

NCBI Accession: NM_018686, NP_061156

UniProt: Q8NFW8