ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 4 (ST8SIA4) (Middle Region) Antikörper

Details zu Produkt Nr. ABIN2783461, Anbieter: Anmelden zum Anzeigen
Antigen
  • SIAT8D
  • PST
  • PST1
  • ST8SIA-IV
  • ST8Sia-IV
  • PST-1
  • SIAT8-D
  • ST8SiaIV
  • Siat8d
  • AI266890
  • ST1A1
  • Stp
  • Stp1
  • ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
  • sulfotransferase family 1A, phenol-preferring, member 1
  • ST8SIA4
  • St8sia4
  • Sult1a1
Epitop
Middle Region
10
9
9
7
4
2
2
2
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus)
31
17
8
5
3
3
3
3
3
2
2
2
2
1
1
1
Wirt
Kaninchen
33
3
Klonalität
Polyklonal
Konjugat
Unkonjugiert
2
2
2
2
2
2
Applikation
Western Blotting (WB)
34
24
16
16
4
1
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen The immunogen is a synthetic peptide directed towards the middle region of human ST8SIA4
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN984508.
Sequenz DVGTKSDFIT MNPSVVQRAF GGFRNESDRE KFVHRLSMLN DSVLWIPAFM
Homologie Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
Produktmerkmale This is a rabbit polyclonal antibody against ST8SIA4. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Andere Bezeichnung ST8SIA4 (ST8SIA4 Antibody Abstract)
Hintergrund ST8SIA4 catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). ST8SIA4, a member of glycosyltransferase family 29, is a type II membrane protein that may be present in the Golgi apparatus.The protein encoded by this gene catalyzes the polycondensation of alpha-2,8-linked sialic acid required for the synthesis of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). The encoded protein, which is a member of glycosyltransferase family 29, is a type II membrane protein that may be present in the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: MGC34450, MGC61459, PST, PST1, SIAT8D, ST8SIA-IV
Protein Interaction Partner: ST8SIA4, NCAM1,
Protein Size: 359
Molekulargewicht 41 kDa
Gen-ID 7903
NCBI Accession NM_005668, NP_005659
UniProt Q92187
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 359 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-ST8 alpha-N-Acetyl-Neuraminide alpha-2,8-Sialyltransferase 4 (ST8SIA4) (Middle Region) antibody (ABIN2783461) WB Suggested Anti-ST8SIA4 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: <...
Allgemeine Veröffentlichungen Schreiber, Giehl, Kastilan, Hasel, Mühlenhoff, Adler, Wedlich, Menke: "Polysialylated NCAM represses E-cadherin-mediated cell-cell adhesion in pancreatic tumor cells." in: Gastroenterology, Vol. 134, Issue 5, pp. 1555-66, 2008 (PubMed).

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