FDFT1 Antikörper (N-Term)

Produktnummer ABIN2783441

Produktdetails anti-FDFT1 Antikörper

Target: FDFT1 (Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FDFT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: HSFLYQPDWR FMESKEKDRQ VLEDFPTISL EFRNLAEKYQ TVIADICRRM

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against FDFT1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FDFT1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 417 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FDFT1

Target: FDFT1 (Farnesyl-Diphosphate Farnesyltransferase 1 (FDFT1))

Andere Bezeichnung: FDFT1 (FDFT1 Produkte)

Synonyme: FDFT1 antikoerper, DKFZp459C1712 antikoerper, SQS antikoerper, SS antikoerper, DGPT antikoerper, ERG9 antikoerper, fdft1 antikoerper, farnesyl-diphosphate farnesyltransferase 1 antikoerper, squalene synthase antikoerper, farnesyl diphosphate farnesyl transferase 1 antikoerper, FDFT1 antikoerper, fdft1 antikoerper, LOC100560926 antikoerper, Fdft1 antikoerper

Hintergrund: FDFT1 is a membrane-associated enzyme located at a branch point in the mevalonate pathway. The protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.This gene encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DGPT, ERG9, SQS, SS
Protein Interaction Partner: UBC, MDM2, FBXO6, EGFR, GLP1R, HDAC10, UBL4A, FN1, UBD, RUVBL2, TMEM43, FAM101A, SHPRH, ARL6IP1, ANXA5, SMNDC1, PSTPIP1, RUVBL1,
Protein Size: 417

Molekulargewicht: 48 kDa

Gen-ID: 2222

NCBI Accession: NM_004462, NP_004453

UniProt: P37268

Pathways: Regulation of Lipid Metabolism by PPARalpha