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TCAP Antikörper (Middle Region)

TCAP Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Ziege, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2783291
  • Target Alle TCAP Antikörper anzeigen
    TCAP (Titin-Cap (Telethonin) (TCAP))
    Bindungsspezifität
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 26
    • 9
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Ziege, Kaninchen
    Wirt
    • 19
    • 8
    Kaninchen
    Klonalität
    • 19
    • 8
    Polyklonal
    Konjugat
    • 20
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TCAP Antikörper ist unkonjugiert
    Applikation
    • 15
    • 8
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Sequenz
    IQLQELLALE TALGGQCVDR QEVAEITKQL PPVVPVSKPG ALRRSLSRSM
    Homologie
    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against TCAP. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human TCAP
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  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 167 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    TCAP (Titin-Cap (Telethonin) (TCAP))
    Andere Bezeichnung
    TCAP (TCAP Produkte)
    Synonyme
    TCAP antikoerper, CMD1N antikoerper, LGMD2G antikoerper, T-cap antikoerper, TELE antikoerper, telethonin antikoerper, AI503981 antikoerper, AJ223855 antikoerper, titin-cap antikoerper, titin-cap (telethonin) antikoerper, titin-cap S homeolog antikoerper, TCAP antikoerper, tcap antikoerper, tcap.S antikoerper, Tcap antikoerper
    Hintergrund
    Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. TCAP is a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in TCAP gene are associated with limb-girdle muscular dystrophy type 2G.Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: CMD1N, LGMD2G, T-cap, TELE, telethonin
    Protein Interaction Partner: TRIM63, TRIM55, RELA, FYN, FAS, ATXN1, MDM2, TTN, PDPK1, MYOZ3, ANKRD2, MYOZ1, MSTN, MYOZ2,
    Protein Size: 167
    Molekulargewicht
    19 kDa
    Gen-ID
    8557
    NCBI Accession
    NM_003673, NP_003664
    UniProt
    O15273
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