ATP5B Antikörper (N-Term)

Produktnummer ABIN2783268

Produktdetails anti-ATP5B Antikörper

Target: ATP5B (ATP Synthase, H+ Transporting, Mitochondrial F1 Complex, beta Polypeptide (ATP5B))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Schwein, Rind (Kuh), Pferd, Kaninchen, Zebrafisch (Danio rerio), Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATP5B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: PIKIPVGPET LGRIMNVIGE PIDERGPIKT KQFAPIHAEA PEFMEMSVEQ

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ATP5B. It was validated on Western Blot and immunohistochemistry. Catalog ABIN973615 can be used a blocking peptide for this product.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ATP5B

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 529 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ATP5B Antikörper (ABIN2783268)

Li, Bates, An, Terry, Wang: "Up-regulation of key microRNAs, and inverse down-regulation of their predicted oxidative phosphorylation target genes, during aging in mouse brain." in: Neurobiology of aging, Vol. 32, Issue 5, pp. 944-55, (2011) (PubMed).

Zischka, Lichtmannegger, Schmitt, Jägemann, Schulz, Wartini, Jennen, Rust, Larochette, Galluzzi, Chajes, Bandow, Gilles, DiSpirito, Esposito, Goettlicher, Summer, Kroemer: "Liver mitochondrial membrane crosslinking and destruction in a rat model of Wilson disease." in: The Journal of clinical investigation, Vol. 121, Issue 4, pp. 1508-18, (2011) (PubMed).

Guo, Prokai-Tatrai, Nguyen, Rauniyar, Ughy, Prokai: "Protein targets for carbonylation by 4-hydroxy-2-nonenal in rat liver mitochondria." in: Journal of proteomics, Vol. 74, Issue 11, pp. 2370-9, (2011) (PubMed).

Details zu ATP5B

Target: ATP5B (ATP Synthase, H+ Transporting, Mitochondrial F1 Complex, beta Polypeptide (ATP5B))

Andere Bezeichnung: ATP5B (ATP5B Produkte)

Synonyme: atpmb antikoerper, atpsb antikoerper, Atpsyn-beta antikoerper, hm:zehn0534 antikoerper, im:6793121 antikoerper, wu:fj38d01 antikoerper, zgc:111961 antikoerper, ATPMB antikoerper, ATPSB antikoerper, ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide antikoerper, ATP synthase subunit beta, mitochondrial antikoerper, ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit antikoerper, ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide S homeolog antikoerper, ATP5B antikoerper, atp5b antikoerper, Atp5b antikoerper, LOC100401662 antikoerper, LOC100635763 antikoerper, atp5b.S antikoerper

Hintergrund: ATP5B is a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). ATP5B is the beta subunit of the catalytic core.This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the beta subunit of the catalytic core. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ATPMB, ATPSB, MGC5231
Protein Interaction Partner: FUS, FDX1, ATP5A1, HUWE1, ATPAF2, TRIM63, TRIM55, SPRTN, STAU1, GRSF1, UBC, MDM2, ASB5, ASB11, SUZ12, RNF2, EZH2, BMI1, GBP1, ADRB2, TERT, vpu, UBL4A, WHSC1, VCAM1, PPP1CC, ITGA4, FN1, ESR1, ATF2, BTK, YWHAE, SUMO2, CA9, FMNL1, ATP5O, ATP6V1B2, ATP5C1, AT
Protein Size: 529

Molekulargewicht: 52 kDa

Gen-ID: 506

NCBI Accession: NM_001686, NP_001677

UniProt: P06576

Pathways: Proton Transport, Ribonucleoside Biosynthetic Process