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AKR1B1 Antikörper (N-Term)

AKR1B1 Reaktivität: Human, Ratte, Maus, Hund, Kaninchen, Rind (Kuh), Zebrafisch (Danio rerio), Meerschweinchen, Pferd, Saccharomyces cerevisiae WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2783262
  • Target Alle AKR1B1 Antikörper anzeigen
    AKR1B1 (Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1))
    Bindungsspezifität
    • 16
    • 15
    • 9
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 67
    • 34
    • 31
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Ratte, Maus, Hund, Kaninchen, Rind (Kuh), Zebrafisch (Danio rerio), Meerschweinchen, Pferd, Saccharomyces cerevisiae
    Wirt
    • 60
    • 12
    • 1
    Kaninchen
    Klonalität
    • 63
    • 10
    Polyklonal
    Konjugat
    • 44
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser AKR1B1 Antikörper ist unkonjugiert
    Applikation
    • 58
    • 26
    • 24
    • 21
    • 14
    • 13
    • 13
    • 11
    • 8
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    ASRLLLNNGA KMPILGLGTW KSPPGQVTEA VKVAIDVGYR HIDCAHVYQN
    Homologie
    Cow: 93%, Dog: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Yeast: 86%, Zebrafish: 91%
    Produktmerkmale
    This is a rabbit polyclonal antibody against AKR1B1. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human AKR1B1
    Top Product
    Discover our top product AKR1B1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 316 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    AKR1B1 (Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) (AKR1B1))
    Andere Bezeichnung
    AKR1B1 (AKR1B1 Produkte)
    Synonyme
    ADR antikoerper, ALDR1 antikoerper, ALR2 antikoerper, AR antikoerper, ALDRED antikoerper, ALR-P-I antikoerper, Akr1b3 antikoerper, Akr1b4 antikoerper, Aldr1 antikoerper, Alr antikoerper, RATALDRED antikoerper, akr1b7 antikoerper, zgc:86611 antikoerper, aldo-keto reductase family 1 member B antikoerper, aldo-keto reductase family 1, member B1 (aldose reductase) antikoerper, aldo-keto reductase family 1, member B1 (aldose reductase) S homeolog antikoerper, AKR1B1 antikoerper, Akr1b1 antikoerper, akr1b1.S antikoerper, akr1b1 antikoerper
    Hintergrund
    AKR1B1 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. There are a few putative pseudogenes for this gene, and one of them has been confirmed and mapped to chromosome 3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: ADR, ALDR1, ALR2, AR, MGC1804
    Protein Interaction Partner: UBC, ASB18, ASB9, ASB5, SMAD1, SORD, SHBG, TFE3,
    Protein Size: 316
    Molekulargewicht
    36 kDa
    Gen-ID
    231
    NCBI Accession
    NM_001628, NP_001619
    UniProt
    P15121
    Pathways
    Metabolism of Steroid Hormones and Vitamin D, C21-Steroid Hormone Metabolic Process, Monocarboxylic Acid Catabolic Process
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