IL28RA Antikörper (N-Term)

Produktnummer ABIN2783214

Produktdetails anti-IL28RA Antikörper

Target: IL28RA (Interleukin 28 Receptor, alpha (Interferon, lambda Receptor) (IL28RA))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL28RA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: EECAGTKELL CSMMCLKKQD LYNKFKGRVR TVSPSSKSPW VESEYLDYLF

Homologie: Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 77%, Rabbit: 86%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against IL28RA. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IL28RA

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 491 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-IL28RA Antikörper (ABIN2783214)

Mucha, Majchrzak, Taciak, Hellmén, Król: "MDSCs mediate angiogenesis and predispose canine mammary tumor cells for metastasis via IL-28/IL-28RA (IFN-?) signaling." in: PLoS ONE, Vol. 9, Issue 7, pp. e103249, (2014) (PubMed).

Details zu IL28RA

Target: IL28RA (Interleukin 28 Receptor, alpha (Interferon, lambda Receptor) (IL28RA))

Andere Bezeichnung: IL28RA (IL28RA Produkte)

Synonyme: IFNLR1 antikoerper, IL28RA antikoerper, crf2/12 antikoerper, ifnlr antikoerper, il-28r1 antikoerper, il28ra antikoerper, licr2 antikoerper, ifnlr1 antikoerper, CRF2-12 antikoerper, Il28ra antikoerper, CRF2/12 antikoerper, IFNLR antikoerper, IL-28R1 antikoerper, LICR2 antikoerper, RGD1562689 antikoerper, interferon lambda receptor 1 antikoerper, interferon, lambda receptor 1 antikoerper, interferon, lambda receptor 1 L homeolog antikoerper, IFNLR1 antikoerper, ifnlr1 antikoerper, ifnlr1.L antikoerper, Ifnlr1 antikoerper

Hintergrund: IL28RA belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. The protein encoded by this gene belongs to the class II cytokine receptor family. This protein forms a receptor complex with interleukine 10 receptor, beta (IL10RB). The receptor complex has been shown to interact with three closely related cytokines, including interleukin 28A (IL28A), interleukin 28B (IL28B), and interleukin 29 (IL29). The expression of all three cytokines can be induced by viral infection. The cells overexpressing this protein have been found to have enhanced responses to IL28A and IL29, but decreased response to IL28B. Three alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: CRF2/12, IFNLR, IFNLR1, LICR2, il-28r1, IL-28R1, IL28RA
Protein Interaction Partner: IFNLR1, IFNL1, IFNL2, LSM8,
Protein Size: 491

Molekulargewicht: 54 kDa

Gen-ID: 163702

NCBI Accession: NM_173064, NP_775087

UniProt: Q5VTX8