FTO Antikörper (Middle Region)

Produktnummer ABIN2782981

Produktdetails anti-FTO Antikörper

Target: FTO (Fat Mass and Obesity-Associated (FTO))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FTO Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: WWCQPMAQLE ALWKKMEGVT NAVLHEVKRE GLPVEQRNEI LTAILASLTA

Homologie: Dog: 86%, Guinea Pig: 100%, Horse: 79%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against FTO. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FTO

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 505 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FTO

Target: FTO (Fat Mass and Obesity-Associated (FTO))

Andere Bezeichnung: FTO (FTO Produkte)

Synonyme: AW743446 antikoerper, mKIAA1752 antikoerper, RGD1305121 antikoerper, FTO, alpha-ketoglutarate dependent dioxygenase antikoerper, fat mass and obesity associated antikoerper, fat mass and obesity associated L homeolog antikoerper, FTO antikoerper, Fto antikoerper, fto.L antikoerper

Hintergrund: The exact function of this gene is not know. Studies in mice suggest that it may be involved in nucleic acid demethylation, and that its mRNA level is regulated by feeding and fasting. Genomewide association studies of type 2 diabetes indicate this gene as a diabetes susceptibility locus. Mutation in this gene has been associated with growth retardation, developmental delay, coarse facies, and early death.
Alias Symbols: KIAA1752, MGC5149
Protein Interaction Partner: UBC, SUMO1, NEDD8, BCCIP, CNDP2, DAK, NDRG1, NPEPPS, SLC9A3R1, CTSA, PEPD, MVD, LDHB, LDHA, EEF2, CKB,
Protein Size: 505

Molekulargewicht: 58 kDa

Gen-ID: 79068

NCBI Accession: NM_001080432, NP_001073901

UniProt: Q9C0B1