ACSL5 Antikörper (Acyl-CoA Synthetase Long-Chain Family Member 5) (C-Term)

Details for Product anti-ACSL5 Antibody No. ABIN2782881, Anbieter: Anmelden zum Anzeigen
Antigen
  • ACSL5
  • acs2
  • acs5
  • facl5
  • ACS2
  • ACS5
  • FACL5
  • 1700030F05Rik
  • Facl5
  • Acs5
  • zgc:92083
  • acyl-CoA synthetase long-chain family member 5
  • ACSL5
  • acsl5
  • LOC100217956
  • Acsl5
Epitop
C-Term
18
7
4
2
2
2
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus), Zebrafisch
52
14
11
2
1
1
1
1
Wirt
Kaninchen
23
20
10
Klonalität
Polyklonal
Konjugat
Dieser ACSL5 Antikörper ist unkonjugiert
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
49
25
10
10
6
1
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human ACSL5
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN972850.
Sequenz ACNYVKLEDV ADMNYFTVNN EGEVCIKGTN VFKGYLKDPE KTQEALDSDG
Homologie Cow: 92%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 93%
Produktmerkmale This is a rabbit polyclonal antibody against ACSL5. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Andere Bezeichnung ACSL5 (ACSL5 Antibody Abstract)
Hintergrund ASCL5 is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene.The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: ACS2, ACS5, FACL5
Protein Interaction Partner: UBC,
Protein Size: 683
Molekulargewicht 76 kDa
Gen-ID 51703
NCBI Accession NM_203379, NP_976313
UniProt Q9ULC5
Forschungsgebiet Signaling, Metabolism
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 683 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Acyl-CoA Synthetase Long-Chain Family Member 5 (ACSL5) (C-Term) antibody (ABIN2782881) anti-Acyl-CoA Synthetase Long-Chain Family Member 5 (ACSL5) (C-Term) antibody
Allgemeine Veröffentlichungen Gaisa, Köster, Reinartz, Ertmer, Ehling, Raupach, Perez-Bouza, Knüchel, Gassler: "Expression of acyl-CoA synthetase 5 in human epidermis." in: Histology and histopathology, Vol. 23, Issue 4, pp. 451-8, 2008 (PubMed).

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