BMP10 Antikörper (N-Term)

Produktnummer ABIN2782813

Produktdetails anti-BMP10 Antikörper

Target: BMP10 (Bone Morphogenetic Protein 10 (BMP10))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Pferd, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BMP10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KFATDRTSMP SANIIRSFKN EDLFSQPVSF NGIRKYPLLF NVSIPHHEEV

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Bmp10. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Rat

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 421 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu BMP10

Target: BMP10 (Bone Morphogenetic Protein 10 (BMP10))

Andere Bezeichnung: Bmp10 (BMP10 Produkte)

Synonyme: BMP10 antikoerper, si:dkey-13n15.5 antikoerper, Bmp10 antikoerper, BMP9 antikoerper, BMP-10 antikoerper, bone morphogenetic protein 10 antikoerper, BMP10 antikoerper, bmp10 antikoerper, LOC662386 antikoerper, Bmp10 antikoerper

Hintergrund: Bmp10 is required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Bmp10 acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Bmp10 inhibits endothelial cell migration and growth.
Alias Symbols: Bmp10
Protein Size: 421

Molekulargewicht: 48 kDa

Gen-ID: 500245

NCBI Accession: NM_001031824, NP_001026994

UniProt: Q4AEG6

Pathways: Hormone Activity, Regulation of Muscle Cell Differentiation